Human echovirus cDNA and Antigen

Human Echovirus is a group of viruses that belong to the genus Enterovirus in the family Picornaviridae. These viruses are common causes of acute respiratory, gastrointestinal and central nervous system infections in humans. The symptoms of echovirus infections can range from mild to severe and can include fever, vomiting, diarrhea, muscle pain, and a rash. Echoviruses are highly contagious and are primarily transmitted through close contact with contaminated fecal matter or through respiratory secretions. There is currently no specific antiviral treatment for echovirus infections, but symptoms can be managed with supportive care.

Human Echovirus antigen refers to any protein or substance found in or produced by the human echovirus. These antigens are used in diagnostic tests to identify the presence of the virus in a person’s blood or body fluids. The detection of echovirus antigens can also help monitor the effectiveness of treatment in people with echovirus infections. Additionally, echovirus antigens are being studied for their potential use in vaccine development to

The Human Echovirus genome is the complete set of genetic information contained in the echovirus. The echovirus genome is composed of a single-stranded RNA molecule and is approximately 7-8 kilobases in length. The genome of echovirus encodes for several viral proteins that are involved in virus replication, immune evasion, and pathogenesis. The study of the echovirus genome has provided important insights into the biology of the virus and has been instrumental in the development of antiviral drugs and vaccines. Here’s what you need to know about these proteins:

Capsid protein VP-1: This protein is a major component of the HEV30 capsid and is responsible for virus assembly and stability. It plays a crucial role in viral entry and attachment to host cells, as it contains the receptor binding site. Additionally, VP-1 is highly immunogenic and is often used as a diagnostic marker for HEV30 infection.

Capsid protein VP1: This protein is also a major structural protein of the HEV30 capsid and is involved in virus assembly and stability. VP1 interacts with other capsid proteins to form a stable capsid structure that protects the viral genome. It is also highly immunogenic and is used as a diagnostic marker for HEV30 infection.

Understanding the functions of VP-1 and VP1 is important for developing effective therapies and vaccines for HEV30. As with other enteroviruses, the transmission of HEV30 can be prevented by practicing good hygiene, such as frequent hand washing and avoiding contact with infected individuals. If you suspect you have been infected with HEV30, seek medical attention immediately to ensure prompt and appropriate treatment.

The use of recombinant proteins/cDNA in academic research and therapeutic applications has skyrocketed. However, in heterologous expression systems, successful recombinant protein expression is dependent on a variety of factors, including codon preference, RNA secondary structure, and GC content. When compared to pre-optimization, more and more experimental results demonstrated that the expression level was dramatically increased, ranging from two to hundred times depending on the gene. Bioclone has created a proprietary technology platform that has resulted in the creation of over 6,000 artificially synthesized codon-optimized cDNA clones (cloned in E. coli expression Vector), which are ready for production of the recombinant proteins.