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Cat# | Product Name | Swiss Prot# | Size | Price (US$) | Order |
PN0854 | Recombinant Protein-Human herpesvirus 1 Capsid protein (Infected cell protein 32) (a.a.51 to 465) | Q1T724 | 100 µg | 1195 | |
PN0855 | Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein B (a.a.31 to 430) | P10211 | 100 µg | 1195 | |
PN0856 | Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein D (a.a.26 to 394) | Q69091 | 100 µg | 1195 | |
PN0857 | Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein G (a.a.31 to 238) | P06484 | 100 µg | 1195 | |
PN0858 | Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein H (a.a.21 to 420) | P06477 | 100 µg | 1195 | |
PN0859 | Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein L (a.a.21 to 224) | P10185 | 100 µg | 1195 | |
PN0860 | Recombinant Protein-Human herpesvirus 1 Glycoprotein C (a.a.24 to 420) | P10228 | 100 µg | 1195 | |
PN0861 | Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein E (a.a.21 to 419) | P04488 | 100 µg | 1195 | |
PN0862 | Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein H (a.a.21 to 400) | P06477 | 100 µg | 1195 | |
PN0863 | Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein I (a.a.21 to 276) | P06487 | 100 µg | 1195 | |
PN0864 | Recombinant Protein-Human herpesvirus 1 Glycoprotein K (a.a.31 to 121) | P68331 | 100 µg | 1195 | |
PN0865 | Recombinant Protein-Human herpesvirus 1 Neurovirulence factor ICP34.5 (a.a.21 to 248) | P36313 | 100 µg | 1195 | |
PN0866 | Recombinant Protein-Human herpesvirus 1 Virion host shutoff protein (a.a.50 to 489) | P10225 | 100 µg | 1195 | |
PN0867 | Recombinant Protein-Human herpesvirus 1 Capsid protein VP26 (a.a.30 to 112) | P10219 | 100 µg | 1195 | |
PN0868 | Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein B (a.a.30 to 330) | P06436 | 100 µg | 1195 | |
PN0869 | Recombinant Protein-Human herpesvirus 2 Immediate-early protein IE4 (IE68) (a.a.21 to 197) | P14379 | 100 µg | 1195 | |
PN0870 | Recombinant Protein-Human herpesvirus 2 VP16 protein (a.a.39 to 490) | Q69113 | 100 µg | 1195 | |
PN0871 | Recombinant Protein-Human herpesvirus 2 Glycoprotein D (a.a.26 to 393) | Q76UG7 | 100 µg | 1195 | |
PN0872 | Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein B (a.a.23 to 450) | P06763 | 100 µg | 1195 | |
PN0873 | Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein D (a.a.26 to 393) | P03172 | 100 µg | 1195 | |
PN0874 | Recombinant Protein-Human herpesvirus 2 Virion host shutoff protein (Vhs) (a.a.45 to 492) | O39988 | 100 µg | 1195 | |
PN0875 | Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein B (a.a.21 to 420) | P08666 | 100 µg | 1195 | |
PN0876 | Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein D (a.a.27 to 393) | Q69467 | 100 µg | 1195 | |
PN0877 | Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein H (a.a.54 to 454) | P89445 | 100 µg | 1195 | |
PN0878 | Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein L (a.a.22 to 224) | P28278 | 100 µg | 1195 | |
PN0879 | Recombinant Protein-Human herpesvirus 2 Glycoprotein C (a.a.31 to 480) | Q89730 | 100 µg | 1195 | |
PN0880 | Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein E (gE-2) (a.a.21 to 414) | P89475 | 100 µg | 1195 | |
PN0881 | Recombinant Protein-Human herpesvirus 2 Neurovirulence factor ICP34.5 (a.a.21 to 261) | P28283 | 100 µg | 1195 | |
PN0882 | Recombinant Protein-Human herpesvirus 2 Serine/threonine-protein kinase 2 (a.a.151 to 518) | P89436 | 100 µg | 1195 | |
PN0883 | Recombinant Protein-Human herpesvirus 2 Tegument protein VP22 (a.a.21 to 300) | P89468 | 100 µg | 1195 | |
PN0884 | Recombinant Protein-Human herpesvirus 3 Envelope glycoprotein gC (a.a.22 to 340) | Q0Q866 | 100 µg | 1195 | |
PN0885 | Recombinant Protein-Human herpesvirus 3 Major capsid protein (a.a.51 to 450) | Q0Q8B2 | 100 µg | 1195 | |
PN0886 | Recombinant Protein-Human herpesvirus 3 Major capsid scaffold protein (a.a.21 to 302) | Q0Q8R5 | 100 µg | 1195 | |
PN0887 | Recombinant Protein-Human herpesvirus 3 Minor capsid protein binding protein (a.a.36 to 483) | Q2PJ44 | 100 µg | 1195 | |
PN0888 | Recombinant Protein-Human herpesvirus 3 Immediate-early protein (a.a.20 to 238) | Q2PJ63 | 100 µg | 1195 | |
PN0889 | Recombinant Protein-Human herpesvirus 3 Envelope glycoprotein gI (a.a.21 to 354) | Q775H9 | 100 µg | 1195 | |
PN0890 | Recombinant Protein-Human herpesvirus 3 strain Ellen Glycoprotein E (a.a.50 to 450) | Q775H2 | 100 µg | 1195 | |
PN0891 | Recombinant Protein-Human herpesvirus 3 strain Ellen Glycoprotein I (a.a.21 to 354) | Q775H3 | 100 µg | 1195 | |
PN0892 | Recombinant Protein-Human herpesvirus 4 type 2 Nuclear antigen-3B (a.a.51 to 450) | Q80P19 | 100 µg | 1195 | |
PN0893 | Recombinant Protein-Human herpesvirus 6 Immediate early region (a.a.51 to 450) | Q69532 | 100 µg | 1195 | |
PN0894 | Recombinant Protein-Human herpesvirus 6A Immediate-early protein 1 (IE1) (a.a.51 to 450) | Q69567 | 100 µg | 1195 | |
PN0895 | Recombinant Protein-Human herpesvirus 6A Triplex capsid protein U56 (a.a.27 to 296) | P24436 | 100 µg | 1195 | |
PN0896 | Recombinant Protein-Human herpesvirus 7 Glycoprotein gp65 (a.a.21 to 468) | Q9QCU9 | 100 µg | 1195 | |
PN0897 | Recombinant Protein-Human herpesvirus 7 Envelope glycoprotein B (a.a.23 to 450) | P52352 | 100 µg | 1195 | |
PN0898 | Recombinant Protein-Human herpesvirus 7 Envelope glycoprotein H (gH) (a.a.17 to 450) | P52353 | 100 µg | 1195 | |
PN0899 | Recombinant Protein-Human herpesvirus 7 Major capsid protein (a.a.51 to 450) | P52347 | 100 µg | 1195 | |
PN0900 | Recombinant Protein-Human herpesvirus 7 Triplex capsid protein VP19C (a.a.43 to 286) | P52349 | 100 µg | 1195 | |
PN0901 | Recombinant Protein-Human herpesvirus 7 gp60 (a.a.21 to 430) | P60506 | 100 µg | 1195 | |
PN0902 | Recombinant Protein-Human herpesvirus 8IE1B protein (a.a.18 to 333) | P90495 | 100 µg | 1195 | |
PN0903 | Recombinant Protein-Human herpesvirus 8 IE1A protein (a.a.21 to 256) | P90489 | 100 µg | 1195 | |
PN0904 | Recombinant Protein-Human herpesvirus 8 Minor capsid protein (a.a.21 to 140) | O89558 | 100 µg | 1195 | |
RPN0854 | cDNA-Human herpesvirus 1 Capsid protein (Infected cell protein 32 (a.a.51 to 465) | Q1T724 | 2 µg | 2070 | |
RPN0855 | cDNA-Human herpesvirus 1 Envelope glycoprotein B (a.a.31 to 430) | P10211 | 2 µg | 1995 | |
RPN0856 | cDNA-Human herpesvirus 1 Envelope glycoprotein D (a.a.26 to 394) | Q69091 | 2 µg | 1840 | |
RPN0857 | cDNA-Human herpesvirus 1 Envelope glycoprotein G (a.a.31 to 238) | P06484 | 2 µg | 1035 | |
RPN0858 | cDNA-Human herpesvirus 1 Envelope glycoprotein H (a.a.21 to 420) | P06477 | 2 µg | 1995 | |
RPN0859 | cDNA-Human herpesvirus 1 Envelope glycoprotein L (a.a.21 to 224) | P10185 | 2 µg | 1015 | |
RPN0860 | cDNA-Human herpesvirus 1 Glycoprotein C (a.a.24 to 420) | P10228 | 2 µg | 1980 | |
RPN0861 | cDNA-Human herpesvirus 1 Envelope glycoprotein E (a.a.21 to 419) | P04488 | 2 µg | 1990 | |
RPN0862 | cDNA-Human herpesvirus 1 Envelope glycoprotein H (a.a.21 to 400) | P06477 | 2 µg | 1895 | |
RPN0863 | cDNA-Human herpesvirus 1 Envelope glycoprotein I (a.a.21 to 276) | P06487 | 2 µg | 1275 | |
RPN0864 | cDNA-Human herpesvirus 1 Glycoprotein K (a.a.31 to 121) | P68331 | 2 µg | 800 | |
RPN0865 | cDNA-Human herpesvirus 1 Neurovirulence factor ICP34.5 (a.a.21 to 248) | P36313 | 2 µg | 1135 | |
RPN0866 | cDNA-Human herpesvirus 1 Virion host shutoff protein (a.a.50 to 489) | P10225 | 2 µg | 2195 | |
RPN0867 | cDNA-Human herpesvirus 1 Capsid protein VP26 (a.a.30 to 112) | P10219 | 2 µg | 800 | |
RPN0868 | cDNA-Human herpesvirus 1 Envelope glycoprotein B (a.a.30 to 330) | P06436 | 2 µg | 1500 | |
RPN0869 | cDNA-Human herpesvirus 2 Immediate-early protein IE4 (IE68) (a.a.21 to 197) | P14379 | 2 µg | 880 | |
RPN0870 | cDNA-Human herpesvirus 2 VP16 protein (a.a.39 to 490) | Q69113 | 2 µg | 2255 | |
RPN0871 | cDNA-Human herpesvirus 2 Glycoprotein D (a.a.26 to 393) | Q76UG7 | 2 µg | 1835 | |
RPN0872 | cDNA-Human herpesvirus 2 Envelope glycoprotein B (a.a.23 to 450) | P06763 | 2 µg | 2135 | |
RPN0873 | cDNA-Human herpesvirus 2 Envelope glycoprotein D (a.a.26 to 393) | P03172 | 2 µg | 1835 | |
RPN0874 | cDNA-Human herpesvirus 2 Virion host shutoff protein (Vhs) (a.a.45 to 492) | O39988 | 2 µg | 2235 | |
RPN0875 | cDNA-Human herpesvirus 2 Envelope glycoprotein B (a.a.21 to 420) | P08666 | 2 µg | 1995 | |
RPN0876 | cDNA-Human herpesvirus 2 Envelope glycoprotein D (a.a.27 to 393) | Q69467 | 2 µg | 1830 | |
RPN0877 | cDNA-Human herpesvirus 2 Envelope glycoprotein H (a.a.54 to 454) | P89445 | 2 µg | 2000 | |
RPN0878 | cDNA-Human herpesvirus 2 Envelope glycoprotein L (a.a.22 to 224) | P28278 | 2 µg | 1010 | |
RPN0879 | cDNA-Human herpesvirus 2 Glycoprotein C (a.a.31 to 480) | Q89730 | 2 µg | 2245 | |
RPN0880 | cDNA-Human herpesvirus 2 Envelope glycoprotein E (gE-2) (a.a.21 to 414) | P89475 | 2 µg | 1965 | |
RPN0881 | cDNA-Human herpesvirus 2 Neurovirulence factor ICP34.5 (a.a.21 to 261) | P28283 | 2 µg | 1200 | |
RPN0882 | cDNA-Human herpesvirus 2 Serine/threonine-protein kinase 2 (a.a.151 to 518) | P89436 | 2 µg | 1835 | |
RPN0883 | cDNA-Human herpesvirus 2 Tegument protein VP22 (a.a.21 to 300) | P89468 | 2 µg | 1395 | |
RPN0884 | cDNA-Human herpesvirus 3 Envelope glycoprotein gC (a.a.22 to 340) | Q0Q866 | 2 µg | 1590 | |
RPN0885 | cDNA-Human herpesvirus 3 Major capsid protein (a.a.51 to 450) | Q0Q8B2 | 2 µg | 1995 | |
RPN0886 | cDNA-Human herpesvirus 3 Major capsid scaffold protein (a.a.21 to 302) | Q0Q8R5 | 2 µg | 1405 | |
RPN0887 | cDNA-Human herpesvirus 3 Minor capsid protein binding protein (a.a.36 to 483) | Q2PJ44 | 2 µg | 2235 | |
RPN0888 | cDNA-Human herpesvirus 3 Immediate-early protein (a.a.20 to 238) | Q2PJ63 | 2 µg | 1090 | |
RPN0889 | cDNA-Human herpesvirus 3 Envelope glycoprotein gI (a.a.21 to 354) | Q775H9 | 2 µg | 1665 | |
RPN0890 | cDNA-Human herpesvirus 3 strain Ellen Glycoprotein E (a.a.50 to 450) | Q775H2 | 2 µg | 2000 | |
RPN0891 | cDNA-Human herpesvirus 3 strain Ellen Glycoprotein I (a.a.21 to 354) | Q775H3 | 2 µg | 1665 | |
RPN0892 | cDNA-Human herpesvirus 4 type 2 Nuclear antigen-3B (a.a.51 to 450) | Q80P19 | 2 µg | 1995 | |
RPN0893 | cDNA-Human herpesvirus 6 Immediate early region (a.a.51 to 450) | Q69532 | 2 µg | 1995 | |
RPN0894 | cDNA-Human herpesvirus 6A Immediate-early protein 1 (IE1) (a.a.51 to 450) | Q69567 | 2 µg | 1995 | |
RPN0895 | cDNA-Human herpesvirus 6A Triplex capsid protein U56 (a.a.27 to 296) | P24436 | 2 µg | 1345 | |
RPN0896 | cDNA-Human herpesvirus 7 Glycoprotein gp65 (a.a.21 to 468) | Q9QCU9 | 2 µg | 2235 | |
RPN0897 | cDNA-Human herpesvirus 7 Envelope glycoprotein B (a.a.23 to 450) | P52352 | 2 µg | 2135 | |
RPN0898 | cDNA-Human herpesvirus 7 Envelope glycoprotein H (gH) (a.a.17 to 450) | P52353 | 2 µg | 2165 | |
RPN0899 | cDNA-Human herpesvirus 7 Major capsid protein (a.a.51 to 450) | P52347 | 2 µg | 1995 | |
RPN0900 | cDNA-Human herpesvirus 7 Triplex capsid protein VP19C (a.a.43 to 286) | P52349 | 2 µg | 1215 | |
RPN0901 | cDNA-Human herpesvirus 7 gp60 (a.a.21 to 430) | P60506 | 2 µg | 2045 | |
RPN0902 | cDNA-Human herpesvirus 8IE1B protein (a.a.18 to 333) | P90495 | 2 µg | 1575 | |
RPN0903 | cDNA-Human herpesvirus 8 IE1A protein (a.a.21 to 256) | P90489 | 2 µg | 1175 | |
RPN0904 | cDNA-Human herpesvirus 8 Minor capsid protein (a.a.21 to 140) | O89558 | 2 µg | 800 |
Human herpesvirus cDNA and recombinant antigen
Human Herpesvirus refers to a group of viruses that cause infections in humans and belong to the herpesviridae family. There are eight known human herpesviruses, including herpes simplex virus 1 and 2, varicella-zoster virus, Epstein-Barr virus, cytomegalovirus, human herpesvirus 6A, 6B, and 7. These viruses can cause a wide range of diseases, including genital herpes, cold sores, chickenpox, mononucleosis, and others. Herpesviruses are highly contagious and are typically spread through direct contact with infected bodily fluids. Once a person is infected, the virus remains in the body for life and can reactivate to cause recurrent outbreaks. There is currently no cure for herpesvirus infections, but antiviral drugs can help control symptoms and reduce the frequency of outbreaks.
Human Herpesvirus antigen refers to any protein or substance found in or produced by human herpesviruses. Herpesvirus antigens are used in diagnostic tests to identify the presence of the virus in a person’s blood or body fluids. The detection of herpesvirus antigens can also help monitor the effectiveness of treatment in people with herpesvirus infections. Additionally, herpesvirus antigens are being studied for their potential use in vaccine development to prevent herpesvirus infections.
The Human Herpesvirus genome refers to the complete set of genetic information contained in the virus. Human herpesviruses have a double-stranded DNA genome that ranges in size from approximately 130 kilobases to more than 220 kilobases. The genome of human herpesviruses encodes for a number of viral proteins that are involved in virus replication, immune evasion, and pathogenesis. The study of human herpesvirus genomes has provided important insights into the biology of these viruses and has been instrumental in the development of antiviral drugs and vaccines.
The virus contains several key proteins that play essential roles in its structure, replication, and pathogenesis. These proteins include:
Capsid protein (Infected cell protein 32, VP26): a protein that makes up the outer layer of the virus particle.
Envelope glycoprotein (B, D, G, H, L): glycoproteins that are found in the viral envelope and are important for viral attachment and entry into host cells.
Glycoprotein (C, D, E, I, K): a type of protein that has a sugar molecule attached to it. In herpesviruses, glycoproteins are found in the viral envelope and play important roles in viral entry, replication, and immune evasion.
Envelope glycoprotein (E, H, I): specific glycoproteins that are found in the herpesvirus envelope and are involved in viral entry and immune evasion.
Neurovirulence factor ICP34.5: a protein that helps herpesviruses evade the host immune response and infect neurons.
Virion host shutoff protein: a protein that is involved in shutting down host protein synthesis during herpesvirus infection.
Immediate-early protein IE4 (IE68): an important regulatory protein that plays a role in activating viral gene expression during the early stages of herpesvirus infection.
VP16: a viral transcription factor that is involved in activating gene expression during the early stages of herpesvirus infection.
Serine/threonine-protein kinase 2: a viral protein kinase that is involved in regulating viral gene expression and replication.
Tegument protein VP22: a viral protein that is found in the tegument layer of the virus particle and is involved in viral replication.
Major capsid protein: a protein that makes up the main structure of the virus particle.
Major capsid scaffold protein: a protein that helps to organize the major capsid proteins into their final structure.
Minor capsid protein binding protein: a protein that is involved in binding to the minor capsid proteins and helping to assemble the virus particle.
Nuclear antigen-3B: a viral protein that is involved in regulating viral gene expression and replication.
Immediate early region: a region of the herpesvirus genome that contains genes that are expressed immediately after infection.
Immediate-early protein 1 (IE1): an important regulatory protein that plays a role in activating viral gene expression during the early stages of herpesvirus infection.
Triplex capsid protein U56: a protein that is involved in the assembly of the virus particle.
VP19C: a viral protein that is involved in capsid assembly and stability.
GP60: a viral glycoprotein that is involved in viral attachment and entry into host cells.
8IE1B protein: a viral protein that is involved in regulating viral gene expression and replication.
IE1A protein: a viral protein that is involved in activating viral gene expression during the early stages of herpesvirus infection.
The use of recombinant proteins/cDNA in academic research and therapeutic applications has skyrocketed. However, in heterologous expression systems, successful recombinant protein expression is dependent on a variety of factors, including codon preference, RNA secondary structure, and GC content. When compared to pre-optimization, more and more experimental results demonstrated that the expression level was dramatically increased, ranging from two to hundred times depending on the gene. Bioclone has created a proprietary technology platform that has resulted in the creation of over 6,000 artificially synthesized codon-optimized cDNA clones (cloned in E.coli expression Vector), which are ready for production of the recombinant proteins.
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