- +1 858 909 0079
- +1 858 909 0057
- [email protected]
- +1 858 909 0079
- [email protected]
Cat. No.
Product Name
Unit Size
Order
Specification
Composition
Magnetic beads grafted with a high density of azide groups on the surface
Number of Beads
~ 1.68 x 109 beads/mg (1μm beads)
~ 5 x 107 beads /mg (5μm beads)
Stability
Short Term (<1 hour): pH 4-11; Long-Term: pH 4-10
Temperature: 4°C -140°C; Most organic solvents
Magnetization
~40-45 EMU/g
Type of Magnetization
Superparamagnetic
Formulation
Lyophilized Powder
Functional Group Density
1μm Magnetic Beads
~40 nmole / mg of Beads
5μm Magnetic Beads
~35 nmole /mg of Beads
Storage
Ship at room temperature, Store at 4°C upon receipt.
BcMag™ Azide-Activated Magnetic Beads are uniform inert silica-enclosed magnetic beads grafted with a high density of azide functional groups on the surface (Fig.1). The beads efficiently enrich alkyne-tagged biomolecules from complex cell lysates via a Cu(I)-catalyzed Alkyne-Azide (CUAAC) reaction. Compared with other affinity resins such as agarose or other polymers beads, the inert silica enclosed magnetic beads offer high stability, low nonspecific binding, and superior handling in protein-based systems. These magnetic beads are an ideal matrix for genomics, proteomics, biomarker discovery, posttranslational modification (PTM) analysis, etc.
The beads work perfectly as affinity resin for capturing azide-tagged biomolecules from complex cell lysate. Add the beads to a sample containing the tagged biomolecules, then mix, incubate, wash and elute the target molecules.
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Easy to use
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More efficient and low nonspecific binding
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Stable covalent bond with minimal ligand leakage
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Produces reusable matrices
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Low nonspecific binding
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