Taenia saginata is a parasitic Tapeworm that infects cattle and humans. It is found worldwide but is particularly common in regions where beef is consumed. In humans, T. saginata infections can cause taeniasis, a condition characterized by mild gastrointestinal symptoms. However, in rare cases, it can lead to more severe complications such as cysticercosis, a serious disease caused by the Tapeworm larvae.

Taenia saginata is a parasitic Tapeworm that contains a protective antigen homologue and oncosphere antigen, which can help stimulate the immune system and provide protection against the Tapeworm. These antigens are important targets for researchers working to develop vaccines against Taenia saginata infections. By understanding the role of these antigens in protecting the Tapeworm from the host’s immune system, we can develop new strategies for preventing and treating these infections.

Protective Antigen Homologue: One of the important features of Taenia saginata is the presence of a protective antigen homologue. This antigen is similar to those found in other Tapeworm species, and it is thought to play a role in protecting the parasite from the host’s immune system. The protective antigen homologue has also been shown to stimulate an immune response in the host, which can provide some level of protection against the Tapeworm.

Oncosphere Antigen: Another important antigen found in Taenia saginata is the oncosphere antigen. This antigen is found on the surface of the Tapeworm’s larvae, which are released from the eggs in the host’s intestine. The oncosphere antigen is thought to play a role in helping the larvae penetrate the intestinal wall and establish an infection. In addition, the oncosphere antigen has also been shown to stimulate an immune response in the host, which can provide some level of protection against the Tapeworm.

Taenia saginata cDNA and recombinant antigen can be used to develop diagnostic tests for Taenia saginata infections. Specifically, Taenia saginata cDNA can be used to develop a PCR-based diagnostic test that can detect the presence of T. saginata DNA. Recombinant antigens can be used to develop an ELISA-based diagnostic test to detect the presence of T. saginata-specific antibodies in a patient’s serum. Combined, these tests can be used to accurately diagnose T. saginata infections.

The use of recombinant proteins/cDNA in academic research and therapeutic applications has skyrocketed. However, in heterologous expression systems, successful recombinant protein expression is dependent on a variety of factors, including codon preference, RNA secondary structure, and GC content. When compared to pre-optimization, more and more experimental results demonstrated that the expression level was dramatically increased, ranging from two to hundred times depending on the gene. Bioclone has created a proprietary technology platform that has resulted in the creation of over 6,000 artificially synthesized codon-optimized cDNA clones (cloned in E. coli expression Vector), which are ready for production of the recombinant proteins.