Products

Plasmodium yoelii cDNA and recombinant antigen

Cat#

Products (Recombinant protein)

Swiss Prot#

Size

Price (US$)

Order

PL0577

Recombinant protein-Plasmodium yoelii nigeriensis Erythrocyte-binding-like protein (a.a.61 to 460)

B5U9X9

100 µg

1195

Order

PL0578

Recombinant protein-Plasmodium yoelii Apical membrane antigen-1 (a.a.18 to 145)

A7LBG0

100 µg

1195

Order

PL0579

Recombinant protein-Plasmodium yoelii Erythrocyte-binding-like protein (a.a.61 to 460)

B5U9X6

100 µg

1195

Order

PL0580

Recombinant protein-Plasmodium yoelii Transmission-blocking target antigen s230 (a.a.61 to 469)

Q7RKE2

100 µg

1195

Order

PL0581

Recombinant protein-Plasmodium yoelii Processed variable antigen-related (a.a.61 to 460)

Q7RB34

100 µg

1195

Order

PL0582

Recombinant protein-Plasmodium yoelii Octapeptide-repeat antigen (a.a.61 to 460)

Q7RBY7

100 µg

1195

Order

PL0583

Recombinant protein-Plasmodium yoelii Tryptophan-threonine-rich antigen (a.a.61 to 424)

Q7RES9

100 µg

1195

Order

PL0584

Recombinant protein-Plasmodium yoelii STARP antigen (a.a.21 to 312)

Q7RSY4

100 µg

1195

Order

PL0585

Recombinant protein-Plasmodium yoelii Secreted blood-stage antigen pAg-3 (a.a.21 to 354)

Q7RIJ4

100 µg

1195

Order

PL0586

Recombinant protein-Plasmodium yoelii Erythrocyte membrane-associated antigen (a.a.61 to 460)

Q7R9A5

100 µg

1195

Order

PL0587

Recombinant protein-Plasmodium yoelii Synthetic antigen (a.a.61 to 467)

Q7RPG4

100 µg

1195

Order

PL0588

Recombinant protein-Plasmodium yoelii Protective antigen-related (a.a.32 to 106)

Q7R947

100 µg

1195

Order

PL0589

Recombinant protein-Plasmodium yoelii Hepatocellular carcinoma-associated antigen 56A (a.a.61 to 460)

Q7RH73

100 µg

1195

Order

PL0590

Recombinant protein-Plasmodium yoelii C-13 antigen-related (a.a.61 to 460)

Q7RLX0

100 µg

1195

Order

PL0591

Recombinant protein-Plasmodium yoelii Synthetic antigen of (a.a.21 to 282)

Q7RJE4

100 µg

1195

Order

PL0592

Recombinant protein-Plasmodium yoelii S-antigen protein (a.a.61 to 460)

Q7RN90

100 µg

1195

Order

PL0593

Recombinant protein-Plasmodium yoelii Seroreactive antigen BMN1-9B-related (a.a.61 to 460)

Q7RIW5

100 µg

1195

Order

PL0594

Recombinant protein-Plasmodium yoelii Malaria antigen-related (a.a.61 to 460)

Q7RGA2

100 µg

1195

Order

PL0595

Recombinant protein-Plasmodium yoelii Apical membrane antigen-1 (a.a.61 to 460)

Q7RP78

100 µg

1195

Order

PL0596

Recombinant protein-Plasmodium yoelii Erythrocyte membrane-associated antigen (a.a.61 to 460)

Q7RAJ7

100 µg

1195

Order

PL0597

Recombinant protein-Plasmodium yoelii hepatocyte erythrocyte protein 17 kDa (a.a.24 to 169)

Q7RGC6

100 µg

1195

Order

PL0598

Recombinant protein-Plasmodium yoelii Mature-parasite-infected erythrocyte surface antigen (a.a.61 to 460)

Q7RBX2

100 µg

1195

Order

PL0599

Recombinant protein-Plasmodium yoelii infected erythrocyte surface antigen (a.a.47 to 343)

Q7RS89

100 µg

1195

Order

PL0600

Recombinant protein-Plasmodium yoelii Sporozoite surface protein 2 (a.a.61 to 460)

Q01443

100 µg

1195

Order

PL0601

Recombinant protein-Plasmodium yoelii C-13 antigen (a.a.61 to 504)

Q7REB1

100 µg

1195

Order

PL0602

Recombinant protein-Plasmodium yoelii Erythrocyte membrane-associated antigen (a.a.61 to 460)

Q7RBN0

100 µg

1195

Order

PL0603

Recombinant protein-Plasmodium yoelii Merozoite surface protein 1-Py230 (a.a.61 to 460)

P13828

100 µg

1195

Order

PL0604

Recombinant protein-Plasmodium yoelii Erythrocyte membrane-associated giant protein antigen (a.a.61 to 460)

Q7RJB3

100 µg

1195

Order

PL0605

Recombinant protein-Plasmodium yoelii Plasmodium falciparum antigen 332 (a.a.61 to 460)

Q7RS33

100 µg

1195

Order

PL0606

Recombinant protein-Plasmodium yoelii Ring-infested erythrocyte surface antigen (a.a.31 to 393)

Q7RC47

100 µg

1195

Order

PL0607

Recombinant protein-Plasmodium yoelii Mature-parasite-infected erythrocyte surface antigen (a.a.61 to 460)

Q7RN42

100 µg

1195

Order

PL0608

Recombinant protein-Plasmodium yoelii Ookinete surface antigen-like protein Pfs28 (a.a.16 to 227)

Q7KJ23

100 µg

1195

Order

PL0609

Recombinant protein-Plasmodium yoelii Mature-parasite-infected erythrocyte surface antigen (a.a.61 to 472)

Q7RME2

100 µg

1195

Order

PL0610

Recombinant protein-Plasmodium yoelii Processed variable antigen (a.a.31 to 414)

Q7RHD2

100 µg

1195

Order

PL0611

Recombinant protein-Plasmodium yoelii Duffy receptor- beta form (a.a.61 to 460)

Q7RFE3

100 µg

1195

Order

PL0612

Recombinant protein-Plasmodium yoelii Synthetic antigen of (a.a.61 to 523)

Q7RFF4

100 µg

1195

Order

PL0613

Recombinant protein-Plasmodium yoelii Transplantation antigen p35b-related (a.a.21 to 212)

Q7RN99

100 µg

1195

Order

PL0614

Recombinant protein-Plasmodium yoelii Ring-infected erythrocyte surface antigen (a.a.31 to 390)

Q7RH32

100 µg

1195

Order

PL0615

Recombinant protein-Plasmodium yoelii Latent nuclear antigen-related (a.a.18 to 139)

Q7RBE8

100 µg

1195

Order

PL0616

Recombinant protein-Plasmodium yoelii Malaria antigen (a.a.61 to 460)

Q7RRF2

100 µg

1195

Order

PL0617

Recombinant protein-Plasmodium yoelii Ring-infested erythrocyte surface antigen (a.a.21 to 259)

Q7RMC1

100 µg

1195

Order

PL0618

Recombinant protein-Plasmodium yoelii Ring-infested erythrocyte surface antigen (a.a.61 to 515)

Q7RCW5

100 µg

1195

Order

PL0619

Recombinant protein-Plasmodium yoelii 19 kDa sporozoite antigen (a.a.24 to 211)

Q7RJQ1

100 µg

1195

Order

PL0620

Recombinant protein-Plasmodium yoelii 41-2 protein antigen-related (a.a.18 to 115)

Q7RE91

100 µg

1195

Order

PL0621

Recombinant protein-Plasmodium yoelii Protective antigen-related (a.a.21 to 316)

Q7RGF9

100 µg

1195

Order

PL0622

Recombinant protein-Plasmodium yoelii Ring-infected erythrocyte surface antigen (a.a.61 to 460)

Q7R903

100 µg

1195

Order

PL0623

Recombinant protein-Plasmodium yoelii Ring-infested erythrocyte surface antigen (a.a.61 to 460)

Q7RLL4

100 µg

1195

Order

RPL0577

cDNA-Plasmodium yoelii nigeriensis Erythrocyte-binding-like protein (a.a.61 to 460)

B5U9X9

2 µg

2394

Order

RPL0578

cDNA-Plasmodium yoelii Apical membrane antigen-1 (a.a.18 to 145)

A7LBG0

2 µg

762

Order

RPL0579

cDNA-Plasmodium yoelii Erythrocyte-binding-like protein (a.a.61 to 460)

B5U9X6

2 µg

2394

Order

RPL0580

cDNA-Plasmodium yoelii Transmission-blocking target antigen s230 (a.a.61 to 469)

Q7RKE2

2 µg

2448

Order

RPL0581

cDNA-Plasmodium yoelii Processed variable antigen-related (a.a.61 to 460)

Q7RB34

2 µg

2394

Order

RPL0582

cDNA-Plasmodium yoelii Octapeptide-repeat antigen (a.a.61 to 460)

Q7RBY7

2 µg

2394

Order

RPL0583

cDNA-Plasmodium yoelii Tryptophan-threonine-rich antigen (a.a.61 to 424)

Q7RES9

2 µg

2178

Order

RPL0584

cDNA-Plasmodium yoelii STARP antigen (a.a.21 to 312)

Q7RSY4

2 µg

1746

Order

RPL0585

cDNA-Plasmodium yoelii Secreted blood-stage antigen pAg-3 (a.a.21 to 354)

Q7RIJ4

2 µg

1998

Order

RPL0586

cDNA-Plasmodium yoelii Erythrocyte membrane-associated antigen (a.a.61 to 460)

Q7R9A5

2 µg

2394

Order

RPL0587

cDNA-Plasmodium yoelii Synthetic antigen (a.a.61 to 467)

Q7RPG4

2 µg

2436

Order

RPL0588

cDNA-Plasmodium yoelii Protective antigen-related (a.a.32 to 106)

Q7R947

2 µg

800

Order

RPL0589

cDNA-Plasmodium yoelii Hepatocellular carcinoma-associated antigen 56A (a.a.61 to 460)

Q7RH73

2 µg

2394

Order

RPL0590

cDNA-Plasmodium yoelii C-13 antigen-related (a.a.61 to 460)

Q7RLX0

2 µg

2394

Order

RPL0591

cDNA-Plasmodium yoelii Synthetic antigen of (a.a.21 to 282)

Q7RJE4

2 µg

1566

Order

RPL0592

cDNA-Plasmodium yoelii S-antigen protein (a.a.61 to 460)

Q7RN90

2 µg

2394

Order

RPL0593

cDNA-Plasmodium yoelii Seroreactive antigen BMN1-9B-related (a.a.61 to 460)

Q7RIW5

2 µg

2394

Order

RPL0594

cDNA-Plasmodium yoelii Malaria antigen-related (a.a.61 to 460)

Q7RGA2

2 µg

2394

Order

RPL0595

cDNA-Plasmodium yoelii Apical membrane antigen-1 (a.a.61 to 460)

Q7RP78

2 µg

2394

Order

RPL0596

cDNA-Plasmodium yoelii Erythrocyte membrane-associated antigen (a.a.61 to 460)

Q7RAJ7

2 µg

2394

Order

RPL0597

cDNA-Plasmodium yoelii hepatocyte erythrocyte protein 17 kDa (a.a.24 to 169)

Q7RGC6

2 µg

870

Order

RPL0598

cDNA-Plasmodium yoelii Mature-parasite-infected erythrocyte surface antigen (a.a.61 to 460)

Q7RBX2

2 µg

2394

Order

RPL0599

cDNA-Plasmodium yoelii infected erythrocyte surface antigen (a.a.47 to 343)

Q7RS89

2 µg

1776

Order

RPL0600

cDNA-Plasmodium yoelii Sporozoite surface protein 2 (a.a.61 to 460)

Q01443

2 µg

2394

Order

RPL0601

cDNA-Plasmodium yoelii C-13 antigen (a.a.61 to 504)

Q7REB1

2 µg

2658

Order

RPL0602

cDNA-Plasmodium yoelii Erythrocyte membrane-associated antigen (a.a.61 to 460)

Q7RBN0

2 µg

2394

Order

RPL0603

cDNA-Plasmodium yoelii Merozoite surface protein 1-Py230 (a.a.61 to 460)

P13828

2 µg

2394

Order

RPL0604

cDNA-Plasmodium yoelii Erythrocyte membrane-associated giant protein antigen (a.a.61 to 460)

Q7RJB3

2 µg

2394

Order

RPL0605

cDNA-Plasmodium yoelii Plasmodium falciparum antigen 332 (a.a.61 to 460)

Q7RS33

2 µg

2394

Order

RPL0606

cDNA-Plasmodium yoelii Ring-infested erythrocyte surface antigen (a.a.31 to 393)

Q7RC47

2 µg

2172

Order

RPL0607

cDNA-Plasmodium yoelii Mature-parasite-infected erythrocyte surface antigen (a.a.61 to 460)

Q7RN42

2 µg

2394

Order

RPL0608

cDNA-Plasmodium yoelii Ookinete surface antigen-like protein Pfs28 (a.a.16 to 227)

Q7KJ23

2 µg

1266

Order

RPL0609

cDNA-Plasmodium yoelii Mature-parasite-infected erythrocyte surface antigen (a.a.61 to 472)

Q7RME2

2 µg

2466

Order

RPL0610

cDNA-Plasmodium yoelii Processed variable antigen (a.a.31 to 414)

Q7RHD2

2 µg

2298

Order

RPL0611

cDNA-Plasmodium yoelii Duffy receptor- beta form (a.a.61 to 460)

Q7RFE3

2 µg

2394

Order

RPL0612

cDNA-Plasmodium yoelii Synthetic antigen of (a.a.61 to 523)

Q7RFF4

2 µg

2772

Order

RPL0613

cDNA-Plasmodium yoelii Transplantation antigen p35b-related (a.a.21 to 212)

Q7RN99

2 µg

1146

Order

RPL0614

cDNA-Plasmodium yoelii Ring-infected erythrocyte surface antigen (a.a.31 to 390)

Q7RH32

2 µg

2154

Order

RPL0615

cDNA-Plasmodium yoelii Latent nuclear antigen-related (a.a.18 to 139)

Q7RBE8

2 µg

726

Order

RPL0616

cDNA-Plasmodium yoelii Malaria antigen (a.a.61 to 460)

Q7RRF2

2 µg

2394

Order

RPL0617

cDNA-Plasmodium yoelii Ring-infested erythrocyte surface antigen (a.a.21 to 259)

Q7RMC1

2 µg

1428

Order

RPL0618

cDNA-Plasmodium yoelii Ring-infested erythrocyte surface antigen (a.a.61 to 515)

Q7RCW5

2 µg

2724

Order

RPL0619

cDNA-Plasmodium yoelii 19 kDa sporozoite antigen (a.a.24 to 211)

Q7RJQ1

2 µg

1122

Order

RPL0620

cDNA-Plasmodium yoelii 41-2 protein antigen-related (a.a.18 to 115)

Q7RE91

2 µg

800

Order

RPL0621

cDNA-Plasmodium yoelii Protective antigen-related (a.a.21 to 316)

Q7RGF9

2 µg

1770

Order

RPL0622

cDNA-Plasmodium yoelii Ring-infected erythrocyte surface antigen (a.a.61 to 460)

Q7R903

2 µg

2394

Order

RPL0623

cDNA-Plasmodium yoelii Ring-infested erythrocyte surface antigen (a.a.61 to 460)

Q7RLL4

2 µg

2394

Order

Plasmodium yoelii cDNA and recombinant antigen

  • Codon-optimized cDNA is cloned into E. coli expression vector with 6x His-tag at N-terminus and ready-to-use for recombinant protein production.
  • Recombinant protein applications: Western Blot may be used for other applications determined by the user.
  • Protein Purity: >90%, as determined by SDS-PAGE under reducing conditions.
  • Protein Activity: N/A
  • Protein Tag:  Contains A 6x histidine tag at N-terminus.
  • Protein Formulation: Liquid
  • Source: Produced from E. coli

Malaria is a life-threatening disease caused by the Plasmodium parasite. While there are five species of Plasmodium that can cause malaria in humans, Plasmodium yoelii is commonly used as a model for studying malaria in animals. Researchers have identified various antigens of Plasmodium yoelii that could potentially be targeted for malaria prevention. In this article, we will explore some of these antigens in detail and how they can be used to prevent malaria.

Nigeriensis Erythrocyte-Binding-Like Protein:

The nigeriensis erythrocyte-binding-like protein (NEBL) is a protein found on the surface of Plasmodium yoelii. It plays a crucial role in the binding of infected red blood cells to uninfected red blood cells, which allows the parasite to evade the immune system. By targeting NEBL, researchers hope to disrupt this binding process and prevent the parasite from spreading.

Apical Membrane Antigen-1:

Another important antigen of Plasmodium yoelii is the apical membrane antigen-1 (AMA-1). This antigen is found on the surface of the parasite and is involved in the invasion of red blood cells. By targeting AMA-1, researchers hope to prevent the parasite from entering red blood cells, which could ultimately prevent the development of malaria.

Transmission-Blocking Target Antigen S230:

The transmission-blocking target antigen S230 (TBS230) is another promising target for malaria prevention. This antigen is involved in the development of the sexual stage of the parasite, which is necessary for transmission between hosts. By targeting TBS230, researchers hope to prevent the parasite from reaching its sexual stage and ultimately prevent transmission.

Processed Variable Antigen-Related:

The processed variable antigen related (PvARP) protein is found on the surface of Plasmodium yoelii and is involved in the binding of infected red blood cells to uninfected red blood cells. By targeting PvARP, researchers hope to disrupt this binding process and prevent the parasite from spreading.

Recombinant Protein-Plasmodium Yoelii Octapeptide-Repeat Antigen (A.a.61 to 460):

The recombinant protein-Plasmodium yoelii octapeptide-repeat antigen (a.a.61 to 460) (PyOPA) is a promising vaccine candidate for malaria prevention. This antigen is found on the surface of the parasite and is involved in the invasion of red blood cells. By targeting PyOPA, researchers hope to prevent the parasite from entering red blood cells, ultimately preventing the development of malaria.

Tryptophan-Threonine-Rich Antigen:

The tryptophan-threonine-rich antigen (TTRA) is another antigen found on the surface of Plasmodium yoelii. This antigen is involved in the invasion of red blood cells and is a promising target for malaria prevention.

STARP Antigen, pAg-3, Erythrocyte Membrane-Associated Antigen, Synthetic Antigen, 56A, C-13 Antigen-Related, S-Antigen Protein, Seroreactive Antigen BMN1-9B-Related, C-13 Antigen, 1-Py230, Ookinete Surface Antigen-Like Protein Pfs28:

Overview of the Key Proteins of Plasmodium Yoelii:

The Plasmodium Yoelii Octapeptide-Repeat Antigen (a.a.61 to 460) is a surface protein of the malaria parasite that plays a critical role in the invasion of red blood cells. Erythrocyte-Binding-Like Protein (EBL) is another essential protein that binds to red blood cells and facilitates invasion by the malaria parasite.

Apical Membrane Antigen-1 (AMA-1) is a surface protein of the malaria parasite that is expressed throughout the life cycle of the parasite and is involved in the invasion of red blood cells. Transmission-Blocking Target Antigen S230 (TBSA) is another surface protein of the malaria parasite that plays a critical role in blocking the transmission of the parasite from one host to another.

Processed Variable Antigen-Related (PvRBP) is a family of surface proteins that are involved in the invasion of red blood cells by the malaria parasite. Tryptophan-Threonine-Rich Antigen (TTRA) is another surface.

Plasmodium Yoelii’s cDNA and recombinant antigens can be used to detect the presence of the parasite in a sample, as well as to track its activity over time. These cDNA and antigens can be used to develop a diagnostic test for malaria, as well as to develop vaccines and therapeutics that can protect against the disease. Additionally, the cDNA and antigens can be used to identify new strains of the parasite, which can help with the development of new treatments.

The use of recombinant proteins/cDNA in academic research and therapeutic applications has skyrocketed. However, in heterologous expression systems, successful recombinant protein expression is dependent on a variety of factors, including codon preference, RNA secondary structure, and GC content. When compared to pre-optimization, more and more experimental results demonstrated that the expression level was dramatically increased, ranging from two to hundred times depending on the gene. Bioclone has created a proprietary technology platform that has resulted in the creation of over 6,000 artificially synthesized codon-optimized cDNA clones (cloned in E. coli expression Vector), which are ready for production of the recombinant proteins.

 

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