Products

Plasmodium vivax cDNA and recombinant antigen

Cat#	Products (Recombinant protein)	Swiss Prot#	Size	Price (US$)	Order
PL0533	Recombinant protein-Plasmodium vivax Tryptophan-rich antigen (a.a.21 to 260)	Q6PVX3	100 µg	1195	Order
PL0534	Recombinant protein-Plasmodium vivax Merozoite surface protein 5 (a.a.31 to 387)	A5KBL6	100 µg	1195	Order
PL0535	Recombinant protein-Plasmodium vivax Serine-repeat antigen 5-SERA (a.a.61 to 460)	A5KBM4	100 µg	1195	Order
PL0536	Recombinant protein-Plasmodium vivax Dihydrofolate reductase (a.a.21 to 237)	Q9TW60	100 µg	1195	Order
PL0537	Recombinant protein-Plasmodium vivax Reticulocyte binding protein 2 (a.a.61 to 460)	Q5DSD7	100 µg	1195	Order
PL0538	Recombinant protein-Plasmodium vivax Proliferating-cell nucleolar antigen p120(a.a.61 to 460)	A5K4V5	100 µg	1195	Order
PL0539	Recombinant protein-Plasmodium vivax 41-2 protein antigen (a.a.21 to 185)	A5K0M4	100 µg	1195	Order
PL0540	Recombinant protein-Plasmodium vivax Tryptophan-rich antigen (Pv-fam-a (a.a.21 to 223)	A5KCP2	100 µg	1195	Order
PL0541	Recombinant protein-Plasmodium vivax Tryptophan-rich antigen (a.a.61 to 460)	A5K745	100 µg	1195	Order
PL0542	Recombinant protein-Plasmodium vivax Serine-repeat antigen-SERA (a.a.61 to 460)	A5KBM1	100 µg	1195	Order
PL0543	Recombinant protein-Plasmodium vivax Serine-repeat antigen 4-SERA (a.a.61 to 460)	A5KBM7	100 µg	1195	Order
PL0544	Recombinant protein-Plasmodium vivax Serine-repeat antigen 1-SERA (a.a. 61 to 460)	A5KBM9	100 µg	1195	Order
PL0545	Recombinant protein-Plasmodium vivax Major blood-stage surface antigen Pv200 (a.a.61 to 460)	Q26194	100 µg	1195	Order
PL0546	Recombinant protein-Plasmodium vivax Merozoite surface protein 1 (a.a. 61 to 460)	Q2I7F0	100 µg	1195	Order
PL0547	Recombinant protein-Plasmodium vivax Duffy receptor (a.a.61 to 460)	A5KDR7	100 µg	1195	Order
PL0548	Recombinant protein-Plasmodium vivax Merozoite surface protein 7-MSP7 (a.a.21 to 377)	A5K7Y9	100 µg	1195	Order
PL0549	Recombinant protein-Plasmodium vivax Tryptophan-threonine-rich antigen (a.a.28 to 313)	A5KCP6	100 µg	1195	Order
PL0550	Recombinant protein-Plasmodium vivax Serine-repeat antigen-SERA (a.a.61 to 460)	A5KBM0	100 µg	1195	Order
PL0551	Recombinant protein-Plasmodium vivax Serine-repeat antigen 4-SERA (V-SERA 4) (a.a.61 to 460)	Q26153	100 µg	1195	Order
PL0552	Recombinant protein-Plasmodium vivax Circumsporozoite-protein related antigen (a.a.22 to 148)	A5K4M8	100 µg	1195	Order
PL0553	Recombinant protein-Plasmodium vivax Circumsporozoite protein (a.a.19 to 377)	A5KB63	100 µg	1195	Order
PL0554	Recombinant protein-Plasmodium vivax Merozoite surface protein 10(a.a.61 to 479)	A5K240	100 µg	1195	Order
PL0555	Recombinant protein-Plasmodium vivax Transmission-blocking target antigen Pfs230 (a.a.14 to 384)	A5KAP6	100 µg	1195	Order
PL0556	Recombinant protein-Plasmodium vivax Merozoite surface protein 3 (MSP3) (a.a.61 to 460)	A5KAV6	100 µg	1195	Order
PL0557	Recombinant protein-Plasmodium vivax Serine-repeat antigen 3-SERA (a.a.61 to 460)	A5KBN0	100 µg	1195	Order
PL0558	Recombinant protein-Plasmodium vivax Merozoite surface protein 4(a.a.19 to 250)	A5KBL7	100 µg	1195	Order
PL0559	Recombinant protein-Plasmodium vivax 41K blood stage antigen 41-3(a.a.31 to 373)	A5K0H7	100 µg	1195	Order
PL0560	Recombinant protein-Plasmodium vivax-Herring worm-protein (a.a.31 to 374)	A5KBH4	100 µg	1195	Order
PL0561	Recombinant protein-Plasmodium vivax Transmission blocking target antigen (Pfs48-45 (a.a.26 to 450)	A5K8A5	100 µg	1195	Order
PL0562	Recombinant protein-Plasmodium vivax Serine-repeat antigen-SERA (a.a.31 to 444)	A5KBM5	100 µg	1195	Order
PL0563	Recombinant protein-Plasmodium vivax Tryptophan rich antigen 39.8 (a.a.35 to 322)	A5K680	100 µg	1195	Order
PL0564	Recombinant protein-Plasmodium vivax Sexual stage antigen s16(a.a.40 to 140)	A5KAN3	100 µg	1195	Order
PL0565	Recombinant protein-Plasmodium vivax QF122 antigen (a.a.61 to 460)	A5K7E3	100 µg	1195	Order
PL0566	Recombinant protein-Plasmodium vivax Rhoptry associated membrane antigen (a.a.61 to 460)	A5KA75	100 µg	1195	Order
PL0567	Recombinant protein-Plasmodium vivax Serine-repeat antigen 2-SERA (a.a.61 to 460)	A5KBN2	100 µg	1195	Order
PL0568	Recombinant protein-Plasmodium vivax Ookinete surface protein Pvs25 (a.a.16 to 219)	Q5EXR1	100 µg	1195	Order
PL0569	Recombinant protein-Plasmodium vivax Erythrocyte membrane-associated antigen (a.a.61 to 460)	A5K660	100 µg	1195	Order
PL0570	Recombinant protein-Plasmodium vivax Merozoite surface protein 8(a.a.31 to 487)	A5KAU1	100 µg	1195	Order
PL0571	Recombinant protein-Plasmodium vivax Serine-repeat antigen 4-SERA (a.a.61 to 460)	A5KBM6	100 µg	1195	Order
PL0572	Recombinant protein-Plasmodium vivax Sexual stage antigen s48-45 (a.a.61 to 460)	A5KBP2	100 µg	1195	Order
PL0573	Recombinant protein-Plasmodium vivax Liver stage antigen (a.a.61 to 460)	A5K4M3	100 µg	1195	Order
PL0574	Recombinant protein-Plasmodium vivax Lactate dehydrogenase (EC 1.1.1.27 (a.a.21 to 299)	Q6JH30	100 µg	1195	Order
PL0575	Recombinant protein-Plasmodium vivax Reticulocyte-binding protein 1 (a.a.61 to 460)	Q00798	100 µg	1195	Order
PL0576	Recombinant protein-Plasmodium vivax Circumsporozoite protein (CS (a.a.21 to 343)	P13826	100 µg	1195	Order
RPL0533	cDNA-Plasmodium vivax Tryptophan-rich antigen (a.a.21 to 260)	Q6PVX3	2 µg	1434	Order
RPL0534	cDNA-Plasmodium vivax Merozoite surface protein 5 (a.a.31 to 387)	A5KBL6	2 µg	2136	Order
RPL0535	cDNA-Plasmodium vivax Serine-repeat antigen 5-SERA (a.a.61 to 460)	A5KBM4	2 µg	2394	Order
RPL0536	cDNA-Plasmodium vivax Dihydrofolate reductase (a.a.21 to 237)	Q9TW60	2 µg	1296	Order
RPL0537	cDNA-Plasmodium vivax Reticulocyte binding protein 2 (a.a.61 to 460)	Q5DSD7	2 µg	2394	Order
RPL0538	cDNA-Plasmodium vivax Proliferating-cell nucleolar antigen p120(a.a.61 to 460)	A5K4V5	2 µg	2394	Order
RPL0539	cDNA-Plasmodium vivax 41-2 protein antigen (a.a.21 to 185)	A5K0M4	2 µg	984	Order
RPL0540	cDNA-Plasmodium vivax Tryptophan-rich antigen (Pv-fam-a (a.a.21 to 223)	A5KCP2	2 µg	1212	Order
RPL0541	cDNA-Plasmodium vivax Tryptophan-rich antigen (a.a.61 to 460)	A5K745	2 µg	2394	Order
RPL0542	cDNA-Plasmodium vivax Serine-repeat antigen-SERA (a.a.61 to 460)	A5KBM1	2 µg	2394	Order
RPL0543	cDNA-Plasmodium vivax Serine-repeat antigen 4-SERA (a.a.61 to 460)	A5KBM7	2 µg	2394	Order
RPL0544	cDNA-Plasmodium vivax Serine-repeat antigen 1-SERA (a.a. 61 to 460)	A5KBM9	2 µg	2394	Order
RPL0545	cDNA-Plasmodium vivax Major blood-stage surface antigen Pv200 (a.a.61 to 460)	Q26194	2 µg	2394	Order
RPL0546	cDNA-Plasmodium vivax Merozoite surface protein 1 (a.a. 61 to 460)	Q2I7F0	2 µg	2394	Order
RPL0547	cDNA-Plasmodium vivax Duffy receptor (a.a.61 to 460)	A5KDR7	2 µg	2394	Order
RPL0548	cDNA-Plasmodium vivax Merozoite surface protein 7-MSP7 (a.a.21 to 377)	A5K7Y9	2 µg	2136	Order
RPL0549	cDNA-Plasmodium vivax Tryptophan-threonine-rich antigen (a.a.28 to 313)	A5KCP6	2 µg	1710	Order
RPL0550	cDNA-Plasmodium vivax Serine-repeat antigen-SERA (a.a.61 to 460)	A5KBM0	2 µg	2394	Order
RPL0551	cDNA-Plasmodium vivax Serine-repeat antigen 4-SERA (V-SERA 4 (a.a.61 to 460)	Q26153	2 µg	2394	Order
RPL0552	cDNA-Plasmodium vivax Circumsporozoite-protein related antigen (a.a.22 to 148)	A5K4M8	2 µg	756	Order
RPL0553	cDNA-Plasmodium vivax Circumsporozoite protein (a.a.19 to 377)	A5KB63	2 µg	2148	Order
RPL0554	cDNA-Plasmodium vivax Merozoite surface protein 10(a.a.61 to 479)	A5K240	2 µg	2508	Order
RPL0555	cDNA-Plasmodium vivax Transmission-blocking target antigen Pfs230 (a.a.14 to 384)	A5KAP6	2 µg	2220	Order
RPL0556	cDNA-Plasmodium vivax Merozoite surface protein 3 (MSP3) (a.a.61 to 460)	A5KAV6	2 µg	2394	Order
RPL0557	cDNA-Plasmodium vivax Serine-repeat antigen 3-SERA (a.a.61 to 460)	A5KBN0	2 µg	2394	Order
RPL0558	cDNA-Plasmodium vivax Merozoite surface protein 4(a.a.19 to 250)	A5KBL7	2 µg	1386	Order
RPL0559	cDNA-Plasmodium vivax 41K blood stage antigen 41-3(a.a.31 to 373)	A5K0H7	2 µg	2052	Order
RPL0560	cDNA-Plasmodium vivax-Herring worm-protein (a.a.31 to 374)	A5KBH4	2 µg	2058	Order
RPL0561	cDNA-Plasmodium vivax Transmission blocking target antigen (Pfs48-45 (a.a.26 to 450)	A5K8A5	2 µg	2544	Order
RPL0562	cDNA-Plasmodium vivax Serine-repeat antigen-SERA (a.a.31 to 444)	A5KBM5	2 µg	2478	Order
RPL0563	cDNA-Plasmodium vivax Tryptophan rich antigen 39.8 (a.a.35 to 322)	A5K680	2 µg	1722	Order
RPL0564	cDNA-Plasmodium vivax Sexual stage antigen s16(a.a.40 to 140)	A5KAN3	2 µg	800	Order
RPL0565	cDNA-Plasmodium vivax QF122 antigen (a.a.61 to 460)	A5K7E3	2 µg	2394	Order
RPL0566	cDNA-Plasmodium vivax Rhoptry associated membrane antigen (a.a.61 to 460)	A5KA75	2 µg	2394	Order
RPL0567	cDNA-Plasmodium vivax Serine-repeat antigen 2-SERA (a.a.61 to 460)	A5KBN2	2 µg	2394	Order
RPL0568	cDNA-Plasmodium vivax Ookinete surface protein Pvs25 (a.a.16 to 219)	Q5EXR1	2 µg	1218	Order
RPL0569	cDNA-Plasmodium vivax Erythrocyte membrane-associated antigen (a.a.61 to 460)	A5K660	2 µg	2394	Order
RPL0570	cDNA-Plasmodium vivax Merozoite surface protein 8(a.a.31 to 487)	A5KAU1	2 µg	2736	Order
RPL0571	cDNA-Plasmodium vivax Serine-repeat antigen 4-SERA (a.a.61 to 460)	A5KBM6	2 µg	2394	Order
RPL0572	cDNA-Plasmodium vivax Sexual stage antigen s48-45 (a.a.61 to 460)	A5KBP2	2 µg	2394	Order
RPL0573	cDNA-Plasmodium vivax Liver stage antigen (a.a.61 to 460)	A5K4M3	2 µg	2394	Order
RPL0574	cDNA-Plasmodium vivax Lactate dehydrogenase (EC 1.1.1.27 (a.a.21 to 299)	Q6JH30	2 µg	1668	Order
RPL0575	cDNA-Plasmodium vivax Reticulocyte-binding protein 1 (a.a.61 to 460)	Q00798	2 µg	2394	Order
RPL0576	cDNA-Plasmodium vivax Circumsporozoite protein (CS (a.a.21 to 343)	P13826	2 µg	1932	Order

Please contact us for a quote on larger sizes …

Plasmodium vivax cDNA and recombinant antigen

Codon-optimized cDNA is cloned into E. coli expression vector with 6x His-tag at N-terminus and ready-to-use for recombinant protein production.
Recombinant protein applications: Western Blot may be used for other applications determined by the user.
Protein Purity: >90%, as determined by SDS-PAGE under reducing conditions.
Protein Activity: N/A
Protein Tag: Contains A 6x histidine tag at N-terminus.
Protein Formulation: Liquid
Source: Produced from E. coli

Plasmodium vivax is one of the five species of Plasmodium parasites that cause malaria in humans. It is a major cause of malaria outside of sub-Saharan Africa and is particularly prevalent in Asia and Latin America. In this article, we will explore some of the key antigens and proteins associated with P. vivax, including the Tryptophan-rich antigen, Merozoite surface proteins 5, 10, and 1, Serine-repeat antigen 5-SERA, Dihydrofolate reductase, Reticulocyte binding protein 2, Proliferating-cell nucleolar antigen p120, 41-2 protein antigen, Serine-repeat antigens SERA 4, 3, and 1, Major blood-stage surface antigen Pv200, Duffy receptor, Merozoite surface protein 7-MSP7, V-SERA 4, Circumsporozoite-protein related antigen, Circumsporozoite protein, Pfs230, and MSP3,41K blood stage antigen 41-3.

Merozoite Surface Proteins (MSPs):
Merozoite Surface Proteins (MSPs) are a group of proteins that are expressed on the surface of the merozoite stage of the Plasmodium parasite. MSPs have been found to play a crucial role in invasion of the red blood cells, which is a crucial step in the pathogenesis of malaria. Some of the key MSPs associated with P. vivax include MSP1, MSP5, MSP7, and MSP10. Of these, MSP1 has been identified as a potential vaccine candidate, as it is known to elicit an immune response in humans.

Serine-repeat Antigens (SERAs):
Serine-repeat antigens (SERAs) are another group of proteins that have been identified as potential vaccine candidates against malaria. These proteins are expressed on the surface of the parasite and are involved in various biological processes, including protein trafficking and invasion of the red blood cells. Some of the key SERAs associated with P. vivax include SERA1, SERA3, SERA4, and SERA5. Of these, SERA1 and SERA4 have been found to elicit an immune response in humans and are being explored as potential vaccine candidates.

Duffy Receptor:
The Duffy receptor is a protein that is found on the surface of red blood cells and is involved in the invasion of the cells by the Plasmodium parasite. Individuals who lack the Duffy receptor are known to be resistant to infection by P. vivax. Understanding the molecular interactions between the Duffy receptor and the parasite can help in the development of strategies to prevent infection by P. vivax.

Circumsporozoite Proteins (CSPs):
Circumsporozoite proteins (CSPs) are a group of proteins that are expressed on the surface of the sporozoite stage of the Plasmodium parasite. CSPs have been identified as potential vaccine candidates against malaria, as they play a crucial role in the invasion of the liver cells by the parasite. Some of the key CSPs associated with P. vivax.

The application of Plasmodium vivax cDNA and recombinant antigen can be in several areas, including:

Diagnosis: cDNA and recombinant antigen can be used to develop diagnostic tests for malaria. For example, specific genes from the parasite can be cloned and used as probes in polymerase chain reaction (PCR) assays to detect the presence of the parasite in blood samples. Similarly, recombinant antigens can be used in serological tests to detect antibodies against the parasite.

Vaccine development: cDNA and recombinant antigen can be used to develop vaccines against malaria. The genes that encode important surface proteins or other antigens of the parasite can be cloned and expressed as recombinant antigens to induce an immune response against the parasite. Similarly, cDNA can be used to identify genes that are important for parasite survival, and these genes can be targeted to develop new vaccine candidates.

Drug discovery: cDNA can be used to identify new drug targets by screening the genome of the parasite for genes that are essential for its survival. Recombinant antigens can also be used to test the efficacy of new drugs by measuring their ability to inhibit the activity of the antigen.

Epidemiological studies: cDNA and recombinant antigen can be used to study the distribution and transmission of P. vivax. The genetic information can be used to identify different strains of the parasite, which can provide insights into the epidemiology of the disease.

The use of recombinant proteins/cDNA in academic research and therapeutic applications has skyrocketed. However, in heterologous expression systems, successful recombinant protein expression is dependent on a variety of factors, including codon preference, RNA secondary structure, and GC content. When compared to pre-optimization, more and more experimental results demonstrated that the expression level was dramatically increased, ranging from two to hundred times depending on the gene. Bioclone has created a proprietary technology platform that has resulted in the creation of over 6,000 artificially synthesized codon-optimized cDNA clones (cloned in E. coli expression Vector), which are ready for production of the recombinant proteins.

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Plasmodium vivax cDNA and recombinant antigen

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