Products

Giardia lamblia cDNA and recombinant antigen

Cat#	Products (Recombinant protein)	Swiss Prot#	Size	Price (US$)	Order
PL0261	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein R1 (a.a.21 to 259)	Q9GQ40	100 µg	1195	Order
PL0262	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein M165 (a.a.61 to 460)	Q9GQ44	100 µg	1195	Order
PL0263	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein M30 (a.a.61 to 435)	Q9GQ41	100 µg	1195	Order
PL0264	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein M20 (a.a.61 to 495)	Q9GQ43	100 µg	1195	Order
PL0265	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein M21-1 (a.a.61 to 460)	Q9GQ45	100 µg	1195	Order
PL0266	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein M21 (a.a.21 to 342)	Q9GQ42	100 µg	1195	Order
PL0267	Recombinant protein-Giardia Lamblia-Giardia intestinalis-Trophozoite surface protein 11 (a.a. 18 to 137)	Q24960	100 µg	1195	Order
PL0268	Recombinant protein-Giardia Lamblia-Giardia intestinalis-Surface protein (a.a.18 to 134)	Q24986	100 µg	1195	Order
PL0269	Recombinant protein-Giardia Lamblia-Giardia intestinalis-Trophozoite surface antigen 417 delta (a.a.17 to 218)	Q24962	100 µg	1195	Order
PL0270	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Major surface-labeled trophozoite antigen 417 (a.a.61 to 460)	P21849	100 µg	1195	Order
PL0271	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein H7-1 (a.a.61 to 460)	Q9U013	100 µg	1195	Order
PL0272	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein H7 (a.a.61 to 460)	Q24992	100 µg	1195	Order
PL0273	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Major surface trophozoite antigen 11 (a.a.61 to 460)	Q03185	100 µg	1195	Order
PL0274	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein 1267 (a.a.61 to 460)	Q07317	100 µg	1195	Order
PL0275	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein VSP136b (a.a.61 to 460)	Q9NGL3	100 µg	1195	Order
PL0276	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Variable surface protein (a.a.61 to 460)	Q8MPM6	100 µg	1195	Order
PL0277	Recombinant protein-Giardia Lamblia-Giardia Intestinalis-Variant surface antigen (a.a.21 to 374)	Q38QK0	100 µg	1195	Order
PL0278	Recombinant protein-Giardia lamblia Surface protein (a.a.1 to 95)	A8BPN6	100 µg	1195	Order
PL0279	Recombinant protein-Giardia lamblia Proliferating cell nuclear antigen (a.a.21 to 299)	A8BIU1	100 µg	1195	Order
PL0280	Recombinant protein-Giardia lamblia Giardia trophozoite antigen GTA-1 (a.a.13 to 181)	A8BPK5	100 µg	1195	Order
PL0281	Recombinant protein-Giardia lamblia Liver stage antigen-like protein (a.a.61 to 460)	A8B344	100 µg	1195	Order
PL0282	Recombinant protein-Giardia lamblia-Herring worm-protein (a.a.34 to 281)	A8BY19	100 µg	1195	Order
PL0283	Recombinant protein-Giardia lamblia Minor histocompatibility antigen H13 (EC 3.4.99.- (a.a.44 to 404)	A8B652	100 µg	1195	Order
PL0284	Recombinant protein-Giardia lamblia Giardia trophozoite antigen GTA-2 (a.a.21 to 236)	A8B291	100 µg	1195	Order
PL0285	Recombinant protein-Giardia lamblia Variant-specific surface protein VSP4A1 (a.a.17 to 128)	A8BLI8	100 µg	1195	Order
PL0286	Recombinant protein-Giardia lamblia Serologically defined colon cancer antigen 1 (a.a.61 to 460)	A8BMB1	100 µg	1195	Order
RPL0261	cDNA-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein R1 (a.a.21 to 259)	Q9GQ40	2 µg	1428	Order
RPL0262	cDNA-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein M165 (a.a.61 to 460)	Q9GQ44	2 µg	2394	Order
RPL0263	cDNA-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein M30 (a.a.61 to 435)	Q9GQ41	2 µg	2244	Order
RPL0264	cDNA-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein M20 (a.a.61 to 495)	Q9GQ43	2 µg	2604	Order
RPL0265	cDNA-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein M21-1 (a.a.61 to 460)	Q9GQ45	2 µg	2394	Order
RPL0266	cDNA-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein M21 (a.a.21 to 342)	Q9GQ42	2 µg	1926	Order
RPL0267	cDNA-Giardia Lamblia-Giardia intestinalis-Trophozoite surface protein 11 (a.a. 18 to 137)	Q24960	2 µg	714	Order
RPL0268	cDNA-Giardia Lamblia-Giardia intestinalis-Surface protein (a.a.18 to 134)	Q24986	2 µg	800	Order
RPL0269	cDNA-Giardia Lamblia-Giardia intestinalis-Trophozoite surface antigen 417 delta (a.a.17 to 218)	Q24962	2 µg	1206	Order
RPL0270	cDNA-Giardia Lamblia-Giardia Intestinalis-Major surface-labeled trophozoite antigen 417 (a.a.61 to 460)	P21849	2 µg	2394	Order
RPL0271	cDNA-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein H7-1 (a.a.61 to 460)	Q9U013	2 µg	2394	Order
RPL0272	cDNA-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein H7 (a.a.61 to 460)	Q24992	2 µg	2394	Order
RPL0273	cDNA-Giardia Lamblia-Giardia Intestinalis-Major surface trophozoite antigen 11 (a.a.61 to 460)	Q03185	2 µg	2394	Order
RPL0274	cDNA-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein 1267 (a.a.61 to 460)	Q07317	2 µg	2394	Order
RPL0275	cDNA-Giardia Lamblia-Giardia Intestinalis-Variant-specific surface protein VSP136b (a.a.61 to 460)	Q9NGL3	2 µg	2394	Order
RPL0276	cDNA-Giardia Lamblia-Giardia Intestinalis-Variable surface protein (a.a.61 to 460)	Q8MPM6	2 µg	2394	Order
RPL0277	cDNA-Giardia Lamblia-Giardia Intestinalis-Variant surface antigen (a.a.21 to 374)	Q38QK0	2 µg	2118	Order
RPL0278	cDNA-Giardia lamblia Surface protein (a.a.1 to 95)	A8BPN6	2 µg	800	Order
RPL0279	cDNA-Giardia lamblia Proliferating cell nuclear antigen (a.a.21 to 299)	A8BIU1	2 µg	1668	Order
RPL0280	cDNA-Giardia lamblia Giardia trophozoite antigen GTA-1 (a.a.13 to 181)	A8BPK5	2 µg	1008	Order
RPL0281	cDNA-Giardia lamblia Liver stage antigen-like protein (a.a.61 to 460)	A8B344	2 µg	2394	Order
RPL0282	cDNA-Giardia lamblia-Herring worm-protein (a.a.34 to 281)	A8BY19	2 µg	1482	Order
RPL0283	cDNA-Giardia lamblia Minor histocompatibility antigen H13 (a.a.44 to 404)	A8B652	2 µg	2160	Order
RPL0284	cDNA-Giardia lamblia Giardia trophozoite antigen GTA-2 (a.a.21 to 236)	A8B291	2 µg	1290	Order
RPL0285	cDNA-Giardia lamblia Variant-specific surface protein VSP4A1 (a.a.17 to 128)	A8BLI8	2 µg	800	Order
RPL0286	cDNA-Giardia lamblia Serologically defined colon cancer antigen 1 (a.a.61 to 460)	A8BMB1	2 µg	2394	Order

Please contact us for a quote on larger sizes …

Giardia lamblia cDNA and recombinant antigen

Codon-optimized cDNA is cloned into E. coli expression vector with 6x His-tag at N-terminus and ready-to-use for recombinant protein production.
Recombinant protein applications: Western Blot may be used for other applications determined by the user.
Protein Purity: >90%, as determined by SDS-PAGE under reducing conditions.
Protein Activity: N/A
Protein Tag: Contains A 6x histidine tag at N-terminus.
Protein Formulation: Liquid
Source: Produced from E. coli

Giardia lamblia, also known as Giardia intestinalis, is a flagellated intestinal parasite that infects humans and animals. It causes a diarrheal disease called giardiasis, which is prevalent in developing countries and is a significant cause of morbidity and mortality in children. This article aims to provide an overview of various surface proteins, antigens, and other biomolecules produced by Giardia lamblia that contribute to its pathogenicity.

Variant-Specific Surface Proteins (VSPs): The VSPs are a family of variable surface proteins that contribute to antigenic variation in Giardia lamblia. These proteins are expressed on the surface of the trophozoites and play a crucial role in immune evasion by the parasite. The VSP family includes several proteins, such as R1 and M165, and specific surface proteins like M30, M20, M21, M21-1, H7-1, H7, 1267, VSP136b, and VSP4A1.

Trophozoite Surface Protein 11 and 417 deltas: Trophozoite surface proteins 11 and 417 delta are two critical biomolecules expressed on the surface of Giardia lamblia trophozoites. These proteins are involved in host-parasite interactions and contribute to the pathogenicity of the parasite.

Labeled Trophozoite Antigen 417: The labeled trophozoite antigen 417 is a highly specific antigen produced by Giardia lamblia. It is commonly used in diagnostic tests to detect the presence of the parasite in stool samples.

Proliferating Cell Nuclear Antigen (PCNA): PCNA is a highly conserved protein expressed by many eukaryotic cells. In Giardia lamblia, PCNA is involved in DNA replication and repair and plays a critical role in the survival of the parasite.

Giardia Trophozoite Antigen GTA-1 and GTA-2: GTA-1 and GTA-2 are surface antigens expressed by Giardia lamblia trophozoites. These antigens play an essential role in host-parasite interactions and contribute to the pathogenicity of the parasite.

Liver Stage Antigen-Like Protein (LSA): LSA is a recently discovered protein expressed by Giardia lamblia that shares significant homology with Plasmodium falciparum’s liver stage antigen-1. LSA is considered a promising target for the development of a Giardia lamblia vaccine.

Minor Histocompatibility Antigen H13: H13 is a minor histocompatibility antigen expressed by Giardia lamblia that has been shown to induce protective immunity against the parasite in animal models.

Serologically Defined Colon Cancer Antigen 1: Serologically defined colon cancer antigen 1 is a protein expressed by Giardia lamblia that shares structural homology with the human colon cancer antigen CO17-1A. This protein is considered a potential target for the development of an anti-giardiasis vaccine.

The use of recombinant proteins/cDNA in academic research and therapeutic applications has skyrocketed. However, in heterologous expression systems, successful recombinant protein expression is dependent on a variety of factors, including codon preference, RNA secondary structure, and GC content. When compared to pre-optimization, more and more experimental results demonstrated that the expression level was dramatically increased, ranging from two to hundred times depending on the gene. Bioclone has created a proprietary technology platform that has resulted in the creation of over 6,000 artificially synthesized codon-optimized cDNA clones (cloned in E. coli expression Vector), which are ready for production of the recombinant proteins.

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Giardia lamblia cDNA and recombinant antigen

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