Products

Mycobacterium tuberculosis cDNA and Antigen

Cat#	Product Name	Swiss Prot#	Size	Price (US$)	Order
PP0588	Recombinant Protein-Mycobacterium tuberculosis 10 kDa chaperonin-Protein (a.a.1 to 100)	P09621	100 µg	1195	Order
PP0589	Recombinant Protein-Mycobacterium tuberculosis 6 kDa early secretory antigenic target ESAT-6 (a.a.19 to 95)	P0A564	100 µg	1195	Order
PP0590	Recombinant Protein-Mycobacterium tuberculosis 45-47 kDa antigen (a.a.39 to 325)	Q50906	100 µg	1195	Order
PP0591	Recombinant Protein-Mycobacterium tuberculosis ahpD (a.a.21 to 177)	P0A5N4	100 µg	1195	Order
PP0592	Recombinant Protein-Mycobacterium tuberculosis AhpC (a.a.33 to 195)	Q7BHK8	100 µg	1195	Order
PP0593	Recombinant Protein-Mycobacterium tuberculosis Antigen MTB48 (a.a.61 to 460)	Q933K8	100 µg	1195	Order
PP0594	Recombinant Protein-Mycobacterium tuberculosis Catalase-peroxidase (a.a.61 to 460)	Q08129	100 µg	1195	Order
PP0595	Recombinant Protein-Mycobacterium tuberculosis Cell surface lipoprotein MPT83 p23 (a.a.38 to 220)	P0A670	100 µg	1195	Order
PP0596	Recombinant Protein-Mycobacterium tuberculosis 2-oxoglutarate dehydrogenase E2 (a.a.61 to 553)	P65633	100 µg	1195	Order
PP0597	Recombinant Protein-Mycobacterium tuberculosis reductase (a.a.28 to 269)	P0A5Y6	100 µg	1195	Order
PP0598	Recombinant Protein-Mycobacterium tuberculosis Secreted antigenic protein MTSA-10 (a.a.14 to 100)	P0A566	100 µg	1195	Order
PP0599	Recombinant Protein-Mycobacterium tuberculosis ESAT-6 esxI Antigen Mtb9.9B (a.a.21 to 94)	P96364	100 µg	1195	Order
PP0600	Recombinant Protein-Mycobacterium tuberculosis Lipoprotein antigen 22 kDa (a.a.45 to 154)	Q8VJV1	100 µg	1195	Order
PP0601	Recombinant Protein-Mycobacterium tuberculosis Rv0092 antigen (a.a.21 to 98)	B8YDF2	100 µg	1195	Order
PP0602	Recombinant Protein-Mycobacterium tuberculosis C antigen cfp2 (a.a.30 to 185)	A2VKA2	100 µg	1195	Order
PP0603	Recombinant Protein-Mycobacterium tuberculosis C protein antigen 6 cfp6 (a.a.23 to 98)	A2VLX4	100 µg	1195	Order
PP0604	Recombinant Protein-Mycobacterium tuberculosis C T-cell antigen TB8.4 (a.a.34 to 110)	A2VH80	100 µg	1195	Order
PP0605	Recombinant Protein-Mycobacterium tuberculosis C Secreted antigen 85-A fbpA (a.a.59 to 363)	A2VMI3	100 µg	1195	Order
PP0606	Recombinant Protein-Mycobacterium tuberculosis C Secreted antigen 85-B fbpB (a.a.40 to 325)	A2VJ01	100 µg	1195	Order
PP0607	Recombinant Protein-Mycobacterium tuberculosis C Mpb51 antigen protein FbpD (a.a.38 to 310)	A2VMI2	100 µg	1195	Order
PP0608	Recombinant Protein-Mycobacterium tuberculosis antigen pra (a.a.34 to 158)	A4KG13	100 µg	1195	Order
PP0609	Recombinant Protein-Mycobacterium tuberculosis Secreted antigen 85-A fbpA (a.a.42 to 338)	A4KMS1	100 µg	1195	Order
RPP0588	cDNA-Mycobacterium tuberculosis 10 kDa chaperonin-Protein (a.a.1 to 100)	P09621	2 µg	800	Order
RPP0589	cDNA-Mycobacterium tuberculosis 6 kDa early secretory antigenic target ESAT-6 (a.a.19 to 95)	P0A564	2 µg	800	Order
RPP0590	cDNA-Mycobacterium tuberculosis 45-47 kDa antigen (a.a.39 to 325)	Q50906	2 µg	1430	Order
RPP0591	cDNA-Mycobacterium tuberculosis ahpD (a.a.21 to 177)	P0A5N4	2 µg	780	Order
RPP0592	cDNA-Mycobacterium tuberculosis AhpC (a.a.33 to 195)	Q7BHK8	2 µg	810	Order
RPP0593	cDNA-Mycobacterium tuberculosis Antigen MTB48 (a.a.61 to 460)	Q933K8	2 µg	1995	Order
RPP0594	cDNA-Mycobacterium tuberculosis Catalase-peroxidase (a.a.61 to 460)	Q08129	2 µg	1995	Order
RPP0595	cDNA-Mycobacterium tuberculosis Cell surface lipoprotein MPT83 p23 (a.a.38 to 220)	P0A670	2 µg	910	Order
RPP0596	cDNA-Mycobacterium tuberculosis 2-oxoglutarate dehydrogenase E2 (a.a.61 to 553)	P65633	2 µg	2460	Order
RPP0597	cDNA-Mycobacterium tuberculosis reductase (a.a.28 to 269)	P0A5Y6	2 µg	1205	Order
RPP0598	cDNA-Mycobacterium tuberculosis Secreted antigenic protein MTSA-10 (a.a.14 to 100)	P0A566	2 µg	800	Order
RPP0599	cDNA-Mycobacterium tuberculosis ESAT-6 esxI Antigen Mtb9.9B (a.a.21 to 94)	P96364	2 µg	800	Order
RPP0600	cDNA-Mycobacterium tuberculosis Lipoprotein antigen 22 kDa (a.a.45 to 154)	Q8VJV1	2 µg	800	Order
RPP0601	cDNA-Mycobacterium tuberculosis Rv0092 antigen (a.a.21 to 98)	B8YDF2	2 µg	800	Order
RPP0602	cDNA-Mycobacterium tuberculosis C antigen cfp2 (a.a.30 to 185)	A2VKA2	2 µg	775	Order
RPP0603	cDNA-Mycobacterium tuberculosis C protein antigen 6 cfp6 (a.a.23 to 98)	A2VLX4	2 µg	800	Order
RPP0604	cDNA-Mycobacterium tuberculosis C T-cell antigen TB8.4 (a.a.34 to 110)	A2VH80	2 µg	800	Order
RPP0605	cDNA-Mycobacterium tuberculosis C Secreted antigen 85-A fbpA (a.a.59 to 363)	A2VMI3	2 µg	1520	Order
RPP0606	cDNA-Mycobacterium tuberculosis C Secreted antigen 85-B fbpB (a.a.40 to 325)	A2VJ01	2 µg	1425	Order
RPP0607	cDNA-Mycobacterium tuberculosis C Mpb51 antigen protein FbpD (a.a.38 to 310)	A2VMI2	2 µg	1360	Order
RPP0608	cDNA-Mycobacterium tuberculosis antigen pra (a.a.34 to 158)	A4KG13	2 µg	620	Order
RPP0609	cDNA-Mycobacterium tuberculosis Secreted antigen 85-A fbpA (a.a.42 to 338)	A4KMS1	2 µg	1480	Order

Please contact us for a quote on larger sizes …

Mycobacterium tuberculosis cDNA and recombinant antigen

Codon-optimized cDNA is cloned into E. coli expression vector with 6x His-tag at N-terminus and ready-to-use for recombinant protein production.
Recombinant protein applications: Western Blot may be used for other applications determined by the user.
Protein Purity: >90%, as determined by SDS-PAGE under reducing conditions.
Protein Activity: N/A
Protein Tag: Contains A 6x histidine tag at N-terminus.
Protein Formulation: Liquid
Source: Produced from E. coli

Mycobacterium tuberculosis is the causative agent of tuberculosis (TB), a serious infectious disease that affects millions of people worldwide. The bacterium possesses various antigens that play important roles in its pathogenesis and immune response. Let’s explore some of these antigens:

10 kDa chaperonin-protein: Also known as the heat shock protein 10 (Hsp10), this antigen is a chaperonin that is involved in protein folding and stress response. It has been shown to interact with the host immune system and modulate the immune response during M. tuberculosis infection.

45-47 kDa antigen: This antigen is a cell wall-associated protein of M. tuberculosis that is recognized by the host immune system during infection. It has been shown to elicit strong immune responses and is often used in diagnostic tests for TB.

AhpD and AhpC: AhpD and AhpC are two antioxidant enzymes of M. tuberculosis that are involved in protecting the bacterium from oxidative stress. They play a role in the ability of M. tuberculosis to survive and persist in the host immune response.

Antigen MTB48: Antigen MTB48 is a secreted protein of M. tuberculosis that is involved in the host-pathogen interaction. It has been shown to stimulate immune responses in infected individuals and is considered to be an important antigen in the context of TB.

Catalase-peroxidase: Catalase-peroxidase is an enzyme of M. tuberculosis that is involved in protecting the bacterium from oxidative damage. It has been shown to play a role in the virulence of M. tuberculosis by modulating the host immune response.

Cell surface lipoprotein MPT83 p23: MPT83 p23 is a cell surface lipoprotein of M. tuberculosis that is involved in the immune response during TB infection. It has been shown to stimulate immune responses and is considered to be an important antigen in the context of TB.

These are just a few examples of the many antigens present in Mycobacterium tuberculosis. These antigens play crucial roles in the pathogenesis and immune response of tuberculosis, including evasion of the host immune system, persistence in the host, and modulation of the immune response.

The use of recombinant proteins/cDNA in academic research and therapeutic applications has skyrocketed. However, in heterologous expression systems, successful recombinant protein expression is dependent on a variety of factors, including codon preference, RNA secondary structure, and GC content. When compared to pre-optimization, more and more experimental results demonstrated that the expression level was dramatically increased, ranging from two to hundred times depending on the gene. Bioclone has created a proprietary technology platform that has resulted in the creation of over 6,000 artificially synthesized codon-optimized cDNA clones (cloned in E. coli expression Vector), which are ready for production of the recombinant proteins.

Mycobacterium tuberculosis cDNA and recombinant antigens are commonly used in diagnosis, vaccine development, and drug discovery. Diagnostic applications include PCR-based assays to detect the presence of M. tuberculosis in clinical samples, such as sputum and other bodily fluids. The recombinant antigens can also be used in ELISA and lateral flow immunoassay formats to detect the presence of antibodies against M. tuberculosis in patient samples. Additionally, recombinant antigens can be used to detect the presence of M. tuberculosis-specific T cells in patient samples.

Vaccine development applications include the use of M. tuberculosis cDNA and recombinant antigens to develop new vaccines against the disease. This includes the development of subunit vaccines and DNA vaccines, which are composed of M. tuberculosis cDNA and recombinant antigens.

Drug discovery applications include the use of M. tuberculosis cDNA and recombinant antigens to identify novel drug targets and to develop new molecules that can inhibit the growth of M. tuberculosis. Additionally, M. tuberculosis cDNA and recombinant antigens can be used to perform high-throughput screenings to identify novel molecules that can inhibit the growth of M. tuberculosis.

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Mycobacterium tuberculosis cDNA and Antigen

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