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Streamline Fingerprint DNA Purification with Bioclone's Revolutionary One-Step System
Streamline Fingerprint DNA Purification with Bioclone's Revolutionary One-Step System
If you work in forensic investigations, you know the value of DNA evidence, especially fingerprint or touch DNA. But obtaining this type of DNA evidence can be challenging, especially when it comes to purifying and extracting the DNA for analysis. Traditional methods are time-consuming and can lead to poor DNA integrity and significant DNA loss. Plus, they often require the use of toxic organic solvents, which can be hazardous to users and the environment.
Thankfully, Bioclone has developed a revolutionary new one-step fingerprint DNA purification system that overcomes these limitations. The BcMag™ One-Step Fingerprint DNA Purification Kit is fast, efficient, and easy to use, with minimal risk of contamination and DNA loss. And it doesn’t require the use of carrier RNA or toxic organic solvents.
Workflow of One-step Fingerprint DNA Purification and purification results (Fig. 1)
1.
Add functional magnetic beads and proteinase K to the sample and incubate at 65°C.
2.
Vortex/pipette the beads with the sample to capture the PCR inhibitors (Fig. 2).
3.
Separate the beads from the sample using a magnet.
4.
Aspirate the supernatant containing the pure, ready-to-use DNA/RNA.
Figure 1 – Workflow
Figure 2 – PCR Inhibitor Removal
The kit uses negative selection chromatography magnetic beads to quickly capture and remove impurities from cell lysate, leaving the DNA untouched. And with only one tube and no liquid transfers, there is a reduced risk of contamination and DNA loss. Plus, the one-step method allows for the processing of hundreds of samples in less than 30 minutes without the need for expensive equipment.
In addition to being faster and more efficient than traditional methods, Bioclone’s One-Step Fingerprint DNA Purification Kit is also more environmentally friendly. It does not require the use of toxic organic solvents, which reduces the environmental impact of the DNA purification process.
Conclusion
In conclusion, the BcMag™ One-Step Fingerprint DNA Purification Kit offers a fast, efficient, and easy-to-use solution for the challenges associated with traditional fingerprint DNA purification methods. The negative selection chromatography magnetic beads quickly capture and remove impurities from cell lysate, leaving the DNA untouched. The result is a high yield of pure DNA that can be used for a wide range of applications in forensic investigations.