Products

Rotavirus cDNA and Antigen

Cat#	Product Name	Swiss Prot#	Size	Price (US$)	Order
PN1405	Recombinant Protein-Rotavirus A VP7 protein (a.a.51 to 326)	A0ESD4	100 µg	1195	Order
PN1406	Recombinant Protein-Rotavirus A VP1 (a.a.51 to 450)	B2BA74	100 µg	1195	Order
PN1407	Recombinant Protein-Rotavirus A VP2 (a.a.51 to 450)	B2BA75	100 µg	1195	Order
PN1408	Recombinant Protein-Rotavirus A VP3 (a.a.51 to 450)	B2BA76	100 µg	1195	Order
PN1409	Recombinant Protein-Rotavirus A NSP5 (a.a.21 to 198)	B2BMF1	100 µg	1195	Order
PN1410	Recombinant Protein-Rotavirus A NSP1 (a.a.31 to 486)	B2BRH0	100 µg	1195	Order
PN1411	Recombinant Protein-Rotavirus A NSP2 (a.a.21 to 317)	B2BRH1	100 µg	1195	Order
PN1412	Recombinant Protein-Rotavirus A NSP3 (a.a.21 to 313)	B2BRH2	100 µg	1195	Order
PN1413	Recombinant Protein-Rotavirus A NSP4 (a.a.51 to 175)	B2BRH3	100 µg	1195	Order
PN1414	Recombinant Protein-Rotavirus A Protein VP3 (a.a.51 to 450)	A7J3A0	100 µg	1195	Order
PN1415	Recombinant Protein-Rotavirus A Outer capsid glycoprotein VP7 (a.a.51 to 326)	Q07156	100 µg	1195	Order
PN1416	Recombinant Protein-Rotavirus A Outer capsid protein VP4 (a.a.51 to 450)	B3SRR9	100 µg	1195	Order
PN1417	Recombinant Protein-Rotavirus A Inner capsid protein VP2 (a.a.51 to 450)	P22672	100 µg	1195	Order
PN1418	Recombinant Protein-Rotavirus A Outer capsid protein VP4 (a.a.51 to 350)	P11196	100 µg	1195	Order
PN1419	Recombinant Protein-Rotavirus A Outer capsid protein VP4 (a.a.51 to 450)	P17465	100 µg	1195	Order
PN1420	Recombinant Protein-Rotavirus A Intermediate capsid protein VP6 (a.a.31 to 397)	A7J3A1	100 µg	1195	Order
PN1421	Recombinant Protein-Rotavirus AInner capsid protein VP2 (a.a.51 to 350)	B1NKT0	100 µg	1195	Order
PN1422	Recombinant Protein-Rotavirus B Intermediate capsid protein VP6 (a.a.31 to 396)	Q45UF5	100 µg	1195	Order
PN1423	Recombinant Protein-Rotavirus B Outer capsid protein (a.a.21 to 249)	C3V9V3	100 µg	1195	Order
PN1424	Recombinant Protein-Rotavirus B Outer capsid protein (a.a.50 to 450)	C3V9V4	100 µg	1195	Order
PN1425	Recombinant Protein-Rotavirus B Inner capsid protein (a.a.25 to 391)	C3V9V5	100 µg	1195	Order
PN1426	Recombinant Protein-Rotavirus C Outer capsid glycoprotein (a.a.21 to 332)	Q67541	100 µg	1195	Order
PN1427	Recombinant Protein-Rotavirus C Intermediate capsid protein VP6 (a.a.21 to 395)	P69482	100 µg	1195	Order
PN1428	Recombinant Protein-Rotavirus C Inner capsid protein VP2 (a.a.50 to 450)	Q91E96	100 µg	1195	Order
PN1429	Recombinant Protein-Rotavirus C Outer capsid protein VP4 (a.a.50 to 450)	Q82040	100 µg	1195	Order
PN1430	Recombinant Protein-Rotavirus C Outer capsid glycoprotein VP7 (a.a.50 to 332)	P30217	100 µg	1195	Order
RPN1405	cDNA-Rotavirus A VP7 protein (a.a.51 to 326)	A0ESD4	2 µg	1375	Order
RPN1406	cDNA-Rotavirus A VP1 (a.a.51 to 450)	B2BA74	2 µg	1995	Order
RPN1407	cDNA-Rotavirus A VP2 (a.a.51 to 450)	B2BA75	2 µg	1995	Order
RPN1408	cDNA-Rotavirus A VP3 (a.a.51 to 450)	B2BA76	2 µg	1995	Order
RPN1409	cDNA-Rotavirus A NSP5 (a.a.21 to 198)	B2BMF1	2 µg	885	Order
RPN1410	cDNA-Rotavirus A NSP1 (a.a.31 to 486)	B2BRH0	2 µg	2275	Order
RPN1411	cDNA-Rotavirus A NSP2 (a.a.21 to 317)	B2BRH1	2 µg	1480	Order
RPN1412	cDNA-Rotavirus A NSP3 (a.a.21 to 313)	B2BRH2	2 µg	1460	Order
RPN1413	cDNA-Rotavirus A NSP4 (a.a.51 to 175)	B2BRH3	2 µg	800	Order
RPN1414	cDNA-Rotavirus A Protein VP3 (a.a.51 to 450)	A7J3A0	2 µg	1995	Order
RPN1415	cDNA-Rotavirus A Outer capsid glycoprotein VP7 (a.a.51 to 326)	Q07156	2 µg	1375	Order
RPN1416	cDNA-Rotavirus A Outer capsid protein VP4 (a.a.51 to 450)	B3SRR9	2 µg	1995	Order
RPN1417	cDNA-Rotavirus A Inner capsid protein VP2 (a.a.51 to 450)	P22672	2 µg	1995	Order
RPN1418	cDNA-Rotavirus A Outer capsid protein VP4 (a.a.51 to 350)	P11196	2 µg	1495	Order
RPN1419	cDNA-Rotavirus A Outer capsid protein VP4 (a.a.51 to 450)	P17465	2 µg	1995	Order
RPN1420	cDNA-Rotavirus A Intermediate capsid protein VP6 (a.a.31 to 397)	A7J3A1	2 µg	1830	Order
RPN1421	cDNA-Rotavirus AInner capsid protein VP2 (a.a.51 to 350)	B1NKT0	2 µg	1495	Order
RPN1422	cDNA-Rotavirus B Intermediate capsid protein VP6 (a.a.31 to 396)	Q45UF5	2 µg	1825	Order
RPN1423	cDNA-Rotavirus B Outer capsid protein (a.a.21 to 249)	C3V9V3	2 µg	1140	Order
RPN1424	cDNA-Rotavirus B Outer capsid protein (a.a.50 to 450)	C3V9V4	2 µg	2000	Order
RPN1425	cDNA-Rotavirus B Inner capsid protein (a.a.25 to 391)	C3V9V5	2 µg	1830	Order
RPN1426	cDNA-Rotavirus C Outer capsid glycoprotein (a.a.21 to 332)	Q67541	2 µg	1555	Order
RPN1427	cDNA-Rotavirus C Intermediate capsid protein VP6 (a.a.21 to 395)	P69482	2 µg	1870	Order
RPN1428	cDNA-Rotavirus C Inner capsid protein VP2 (a.a.50 to 450)	Q91E96	2 µg	2000	Order
RPN1429	cDNA-Rotavirus C Outer capsid protein VP4 (a.a.50 to 450)	Q82040	2 µg	2000	Order
RPN1430	cDNA-Rotavirus C Outer capsid glycoprotein VP7 (a.a.50 to 332)	P30217	2 µg	1410	Order

Please contact us for a quote on larger sizes …

Rotavirus cDNA and recombinant antigen

Codon-optimized cDNA is cloned into E. coli expression vector with 6x His-tag at N-terminus and ready-to-use for recombinant protein production.
Recombinant protein applications: Western Blot may be used for other applications determined by the user.
Protein Purity: >90%, as determined by SDS-PAGE under reducing conditions.
Protein Activity: N/A
Protein Tag: Contains A 6x histidine tag at N-terminus.
Protein Formulation: Liquid
Source: Produced from E. coli

Rotavirus is a highly contagious virus that can cause acute gastroenteritis in humans and animals. It is the most common cause of severe diarrhea in infants and young children worldwide. Symptoms can include fever, vomiting, abdominal pain, and watery diarrhea. Treatment typically involves supportive care, such as hydration and electrolyte replacement, and in some cases, antiviral medications. Vaccines are available to help prevent rotavirus infection.

Rotavirus is a type of virus that can cause severe diarrhea and dehydration in infants and young children. Rotavirus antigen is a substance that is used to detect the presence of the rotavirus in a patient’s sample. It can be detected in stool, saliva, and throat swabs. The antigen can be detected by several different methods, including enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR).

The genome of rotaviruses consists of 11 double-stranded RNA segments. The genome encodes six structural proteins and six nonstructural proteins. The structural proteins include the major outer capsid protein VP7, the minor outer capsid protein VP4, the inner capsid proteins VP6 and VP2, the spike proteins VP1 and VP3, and the nonstructural proteins NSP1–NSP6. The genome of rotaviruses is also characterized by genomic segment size variation and variable gene order.

Some important proteins of rotavirus are VP7, VP1, VP2, VP3, NSP5, NSP1, NSP2, NSP3, NSP4, outer capsid glycoprotein VP7 and VP4, inner capsid protein VP2, intermediate capsid protein VP6. These proteins play important roles in the life cycle of the virus, including viral entry, replication, assembly, and release. VP7 and VP4 are the major antigenic determinants of the virus and are important in vaccine development.

NSP5 is an important non-structural protein that plays a role in the assembly of the viral particle. NSP1, NSP2, NSP3, and NSP4 are also non-structural proteins that are involved in various steps of the virus life cycle, including genome replication, modulation of host cell processes, and assembly of the virus particles.

VP7 is the outer capsid glycoprotein of the virus, which is involved in viral entry and host cell recognition. VP4 is also a glycoprotein that plays a key role in viral entry and is the major target for neutralizing antibodies. VP2 is the inner capsid protein and VP6 is the intermediate capsid protein, which play a role in the assembly and stability of the viral particle.

Understanding the function of these proteins is important for the development of effective treatments and vaccines for rotavirus infections.

The use of recombinant proteins/cDNA in academic research and therapeutic applications has skyrocketed. However, in heterologous expression systems, successful recombinant protein expression is dependent on a variety of factors, including codon preference, RNA secondary structure, and GC content. When compared to pre-optimization, more and more experimental results demonstrated that the expression level was dramatically increased, ranging from two to hundred times depending on the gene. Bioclone has created a proprietary technology platform that has resulted in the creation of over 6,000 artificially synthesized codon-optimized cDNA clones (cloned in E. coli expression Vector), which are ready for production of the recombinant proteins.

Bioclone

Products

Rotavirus cDNA and Antigen

Learn More

Bioclone Inc.

Welcome to BitClone