Rat coronavirus cDNA and Antigen

Rat coronavirus is a member of the Coronaviridae family and can cause respiratory and gastrointestinal infections in rats. The virus has several important proteins that are critical for its replication and pathogenesis.

Protein I is a structural protein that is important for the stability of the viral particle. The 12.7 kDa accessory protein is involved in virus assembly and is also important for the stability of the viral particle. The non-structural protein 2a is involved in viral replication and may play a role in pathogenesis.

The spike proteins S1 and S2 are important for virus entry into host cells and are also important targets for host immune responses. The matrix glycoprotein is a structural protein that plays a key role in virus assembly and is important for the stability of the viral particle. The hemagglutinin-esterase is a glycoprotein that is involved in virus entry into host cells and may also play a role in pathogenesis.

Research on Rat coronavirus is ongoing and focused on understanding the roles of these proteins in the replication and pathogenesis of the virus, as well as developing effective treatments and prevention strategies for Rat coronavirus infections. By studying these proteins and their interactions, researchers hope to gain a better understanding of how the virus works and how it can be effectively targeted to prevent or treat infections.

The use of recombinant proteins/cDNA in academic research and therapeutic applications has skyrocketed. However, in heterologous expression systems, successful recombinant protein expression is dependent on a variety of factors, including codon preference, RNA secondary structure, and GC content. When compared to pre-optimization, more and more experimental results demonstrated that the expression level was dramatically increased, ranging from two to hundred times depending on the gene. Bioclone has created a proprietary technology platform that has resulted in the creation of over 6,000 artificially synthesized codon-optimized cDNA clones (cloned in E. coli expression Vector), which are ready for production of the recombinant proteins.