Products

Human herpesvirus cDNA and Antigen

Cat#

Product Name

Swiss Prot#

Size

Price (US$)

Order

PN0854

Recombinant Protein-Human herpesvirus 1 Capsid protein (Infected cell protein 32) (a.a.51 to 465)

Q1T724

100 µg

1195

Order

PN0855

Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein B (a.a.31 to 430)

P10211

100 µg

1195

Order

PN0856

Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein D (a.a.26 to 394)

Q69091

100 µg

1195

Order

PN0857

Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein G (a.a.31 to 238)

P06484

100 µg

1195

Order

PN0858

Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein H (a.a.21 to 420)

P06477

100 µg

1195

Order

PN0859

Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein L (a.a.21 to 224)

P10185

100 µg

1195

Order

PN0860

Recombinant Protein-Human herpesvirus 1 Glycoprotein C (a.a.24 to 420)

P10228

100 µg

1195

Order

PN0861

Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein E (a.a.21 to 419)

P04488

100 µg

1195

Order

PN0862

Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein H (a.a.21 to 400)

P06477

100 µg

1195

Order

PN0863

Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein I (a.a.21 to 276)

P06487

100 µg

1195

Order

PN0864

Recombinant Protein-Human herpesvirus 1 Glycoprotein K (a.a.31 to 121)

P68331

100 µg

1195

Order

PN0865

Recombinant Protein-Human herpesvirus 1 Neurovirulence factor ICP34.5 (a.a.21 to 248)

P36313

100 µg

1195

Order

PN0866

Recombinant Protein-Human herpesvirus 1 Virion host shutoff protein (a.a.50 to 489)

P10225

100 µg

1195

Order

PN0867

Recombinant Protein-Human herpesvirus 1 Capsid protein VP26 (a.a.30 to 112)

P10219

100 µg

1195

Order

PN0868

Recombinant Protein-Human herpesvirus 1 Envelope glycoprotein B (a.a.30 to 330)

P06436

100 µg

1195

Order

PN0869

Recombinant Protein-Human herpesvirus 2 Immediate-early protein IE4 (IE68) (a.a.21 to 197)

P14379

100 µg

1195

Order

PN0870

Recombinant Protein-Human herpesvirus 2 VP16 protein (a.a.39 to 490)

Q69113

100 µg

1195

Order

PN0871

Recombinant Protein-Human herpesvirus 2 Glycoprotein D (a.a.26 to 393)

Q76UG7

100 µg

1195

Order

PN0872

Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein B (a.a.23 to 450)

P06763

100 µg

1195

Order

PN0873

Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein D (a.a.26 to 393)

P03172

100 µg

1195

Order

PN0874

Recombinant Protein-Human herpesvirus 2 Virion host shutoff protein (Vhs) (a.a.45 to 492)

O39988

100 µg

1195

Order

PN0875

Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein B (a.a.21 to 420)

P08666

100 µg

1195

Order

PN0876

Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein D (a.a.27 to 393)

Q69467

100 µg

1195

Order

PN0877

Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein H (a.a.54 to 454)

P89445

100 µg

1195

Order

PN0878

Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein L (a.a.22 to 224)

P28278

100 µg

1195

Order

PN0879

Recombinant Protein-Human herpesvirus 2 Glycoprotein C (a.a.31 to 480)

Q89730

100 µg

1195

Order

PN0880

Recombinant Protein-Human herpesvirus 2 Envelope glycoprotein E (gE-2) (a.a.21 to 414)

P89475

100 µg

1195

Order

PN0881

Recombinant Protein-Human herpesvirus 2 Neurovirulence factor ICP34.5 (a.a.21 to 261)

P28283

100 µg

1195

Order

PN0882

Recombinant Protein-Human herpesvirus 2 Serine/threonine-protein kinase 2 (a.a.151 to 518)

P89436

100 µg

1195

Order

PN0883

Recombinant Protein-Human herpesvirus 2 Tegument protein VP22 (a.a.21 to 300)

P89468

100 µg

1195

Order

PN0884

Recombinant Protein-Human herpesvirus 3 Envelope glycoprotein gC (a.a.22 to 340)

Q0Q866

100 µg

1195

Order

PN0885

Recombinant Protein-Human herpesvirus 3 Major capsid protein (a.a.51 to 450)

Q0Q8B2

100 µg

1195

Order

PN0886

Recombinant Protein-Human herpesvirus 3 Major capsid scaffold protein (a.a.21 to 302)

Q0Q8R5

100 µg

1195

Order

PN0887

Recombinant Protein-Human herpesvirus 3 Minor capsid protein binding protein (a.a.36 to 483)

Q2PJ44

100 µg

1195

Order

PN0888

Recombinant Protein-Human herpesvirus 3 Immediate-early protein (a.a.20 to 238)

Q2PJ63

100 µg

1195

Order

PN0889

Recombinant Protein-Human herpesvirus 3 Envelope glycoprotein gI (a.a.21 to 354)

Q775H9

100 µg

1195

Order

PN0890

Recombinant Protein-Human herpesvirus 3 strain Ellen Glycoprotein E (a.a.50 to 450)

Q775H2

100 µg

1195

Order

PN0891

Recombinant Protein-Human herpesvirus 3 strain Ellen Glycoprotein I (a.a.21 to 354)

Q775H3

100 µg

1195

Order

PN0892

Recombinant Protein-Human herpesvirus 4 type 2 Nuclear antigen-3B (a.a.51 to 450)

Q80P19

100 µg

1195

Order

PN0893

Recombinant Protein-Human herpesvirus 6 Immediate early region (a.a.51 to 450)

Q69532

100 µg

1195

Order

PN0894

Recombinant Protein-Human herpesvirus 6A Immediate-early protein 1 (IE1) (a.a.51 to 450)

Q69567

100 µg

1195

Order

PN0895

Recombinant Protein-Human herpesvirus 6A Triplex capsid protein U56 (a.a.27 to 296)

P24436

100 µg

1195

Order

PN0896

Recombinant Protein-Human herpesvirus 7 Glycoprotein gp65 (a.a.21 to 468)

Q9QCU9

100 µg

1195

Order

PN0897

Recombinant Protein-Human herpesvirus 7 Envelope glycoprotein B (a.a.23 to 450)

P52352

100 µg

1195

Order

PN0898

Recombinant Protein-Human herpesvirus 7 Envelope glycoprotein H (gH) (a.a.17 to 450)

P52353

100 µg

1195

Order

PN0899

Recombinant Protein-Human herpesvirus 7 Major capsid protein (a.a.51 to 450)

P52347

100 µg

1195

Order

PN0900

Recombinant Protein-Human herpesvirus 7 Triplex capsid protein VP19C (a.a.43 to 286)

P52349

100 µg

1195

Order

PN0901

Recombinant Protein-Human herpesvirus 7 gp60 (a.a.21 to 430)

P60506

100 µg

1195

Order

PN0902

Recombinant Protein-Human herpesvirus 8IE1B protein (a.a.18 to 333)

P90495

100 µg

1195

Order

PN0903

Recombinant Protein-Human herpesvirus 8 IE1A protein (a.a.21 to 256)

P90489

100 µg

1195

Order

PN0904

Recombinant Protein-Human herpesvirus 8 Minor capsid protein (a.a.21 to 140)

O89558

100 µg

1195

Order

RPN0854

cDNA-Human herpesvirus 1 Capsid protein (Infected cell protein 32 (a.a.51 to 465)

Q1T724

2 µg

2070

Order

RPN0855

cDNA-Human herpesvirus 1 Envelope glycoprotein B (a.a.31 to 430)

P10211

2 µg

1995

Order

RPN0856

cDNA-Human herpesvirus 1 Envelope glycoprotein D (a.a.26 to 394)

Q69091

2 µg

1840

Order

RPN0857

cDNA-Human herpesvirus 1 Envelope glycoprotein G (a.a.31 to 238)

P06484

2 µg

1035

Order

RPN0858

cDNA-Human herpesvirus 1 Envelope glycoprotein H (a.a.21 to 420)

P06477

2 µg

1995

Order

RPN0859

cDNA-Human herpesvirus 1 Envelope glycoprotein L (a.a.21 to 224)

P10185

2 µg

1015

Order

RPN0860

cDNA-Human herpesvirus 1 Glycoprotein C (a.a.24 to 420)

P10228

2 µg

1980

Order

RPN0861

cDNA-Human herpesvirus 1 Envelope glycoprotein E (a.a.21 to 419)

P04488

2 µg

1990

Order

RPN0862

cDNA-Human herpesvirus 1 Envelope glycoprotein H (a.a.21 to 400)

P06477

2 µg

1895

Order

RPN0863

cDNA-Human herpesvirus 1 Envelope glycoprotein I (a.a.21 to 276)

P06487

2 µg

1275

Order

RPN0864

cDNA-Human herpesvirus 1 Glycoprotein K (a.a.31 to 121)

P68331

2 µg

800

Order

RPN0865

cDNA-Human herpesvirus 1 Neurovirulence factor ICP34.5 (a.a.21 to 248)

P36313

2 µg

1135

Order

RPN0866

cDNA-Human herpesvirus 1 Virion host shutoff protein (a.a.50 to 489)

P10225

2 µg

2195

Order

RPN0867

cDNA-Human herpesvirus 1 Capsid protein VP26 (a.a.30 to 112)

P10219

2 µg

800

Order

RPN0868

cDNA-Human herpesvirus 1 Envelope glycoprotein B (a.a.30 to 330)

P06436

2 µg

1500

Order

RPN0869

cDNA-Human herpesvirus 2 Immediate-early protein IE4 (IE68) (a.a.21 to 197)

P14379

2 µg

880

Order

RPN0870

cDNA-Human herpesvirus 2 VP16 protein (a.a.39 to 490)

Q69113

2 µg

2255

Order

RPN0871

cDNA-Human herpesvirus 2 Glycoprotein D (a.a.26 to 393)

Q76UG7

2 µg

1835

Order

RPN0872

cDNA-Human herpesvirus 2 Envelope glycoprotein B (a.a.23 to 450)

P06763

2 µg

2135

Order

RPN0873

cDNA-Human herpesvirus 2 Envelope glycoprotein D (a.a.26 to 393)

P03172

2 µg

1835

Order

RPN0874

cDNA-Human herpesvirus 2 Virion host shutoff protein (Vhs) (a.a.45 to 492)

O39988

2 µg

2235

Order

RPN0875

cDNA-Human herpesvirus 2 Envelope glycoprotein B (a.a.21 to 420)

P08666

2 µg

1995

Order

RPN0876

cDNA-Human herpesvirus 2 Envelope glycoprotein D (a.a.27 to 393)

Q69467

2 µg

1830

Order

RPN0877

cDNA-Human herpesvirus 2 Envelope glycoprotein H (a.a.54 to 454)

P89445

2 µg

2000

Order

RPN0878

cDNA-Human herpesvirus 2 Envelope glycoprotein L (a.a.22 to 224)

P28278

2 µg

1010

Order

RPN0879

cDNA-Human herpesvirus 2 Glycoprotein C (a.a.31 to 480)

Q89730

2 µg

2245

Order

RPN0880

cDNA-Human herpesvirus 2 Envelope glycoprotein E (gE-2) (a.a.21 to 414)

P89475

2 µg

1965

Order

RPN0881

cDNA-Human herpesvirus 2 Neurovirulence factor ICP34.5 (a.a.21 to 261)

P28283

2 µg

1200

Order

RPN0882

cDNA-Human herpesvirus 2 Serine/threonine-protein kinase 2 (a.a.151 to 518)

P89436

2 µg

1835

Order

RPN0883

cDNA-Human herpesvirus 2 Tegument protein VP22 (a.a.21 to 300)

P89468

2 µg

1395

Order

RPN0884

cDNA-Human herpesvirus 3 Envelope glycoprotein gC (a.a.22 to 340)

Q0Q866

2 µg

1590

Order

RPN0885

cDNA-Human herpesvirus 3 Major capsid protein (a.a.51 to 450)

Q0Q8B2

2 µg

1995

Order

RPN0886

cDNA-Human herpesvirus 3 Major capsid scaffold protein (a.a.21 to 302)

Q0Q8R5

2 µg

1405

Order

RPN0887

cDNA-Human herpesvirus 3 Minor capsid protein binding protein (a.a.36 to 483)

Q2PJ44

2 µg

2235

Order

RPN0888

cDNA-Human herpesvirus 3 Immediate-early protein (a.a.20 to 238)

Q2PJ63

2 µg

1090

Order

RPN0889

cDNA-Human herpesvirus 3 Envelope glycoprotein gI (a.a.21 to 354)

Q775H9

2 µg

1665

Order

RPN0890

cDNA-Human herpesvirus 3 strain Ellen Glycoprotein E (a.a.50 to 450)

Q775H2

2 µg

2000

Order

RPN0891

cDNA-Human herpesvirus 3 strain Ellen Glycoprotein I (a.a.21 to 354)

Q775H3

2 µg

1665

Order

RPN0892

cDNA-Human herpesvirus 4 type 2 Nuclear antigen-3B (a.a.51 to 450)

Q80P19

2 µg

1995

Order

RPN0893

cDNA-Human herpesvirus 6 Immediate early region (a.a.51 to 450)

Q69532

2 µg

1995

Order

RPN0894

cDNA-Human herpesvirus 6A Immediate-early protein 1 (IE1) (a.a.51 to 450)

Q69567

2 µg

1995

Order

RPN0895

cDNA-Human herpesvirus 6A Triplex capsid protein U56 (a.a.27 to 296)

P24436

2 µg

1345

Order

RPN0896

cDNA-Human herpesvirus 7 Glycoprotein gp65 (a.a.21 to 468)

Q9QCU9

2 µg

2235

Order

RPN0897

cDNA-Human herpesvirus 7 Envelope glycoprotein B (a.a.23 to 450)

P52352

2 µg

2135

Order

RPN0898

cDNA-Human herpesvirus 7 Envelope glycoprotein H (gH) (a.a.17 to 450)

P52353

2 µg

2165

Order

RPN0899

cDNA-Human herpesvirus 7 Major capsid protein (a.a.51 to 450)

P52347

2 µg

1995

Order

RPN0900

cDNA-Human herpesvirus 7 Triplex capsid protein VP19C (a.a.43 to 286)

P52349

2 µg

1215

Order

RPN0901

cDNA-Human herpesvirus 7 gp60 (a.a.21 to 430)

P60506

2 µg

2045

Order

RPN0902

cDNA-Human herpesvirus 8IE1B protein (a.a.18 to 333)

P90495

2 µg

1575

Order

RPN0903

cDNA-Human herpesvirus 8 IE1A protein (a.a.21 to 256)

P90489

2 µg

1175

Order

RPN0904

cDNA-Human herpesvirus 8 Minor capsid protein (a.a.21 to 140)

O89558

2 µg

800

Order

Human herpesvirus cDNA and recombinant antigen

  • Codon-optimized cDNA is cloned into E. coli expression vector with 6x His-tag at N-terminus and ready-to-use for recombinant protein production.
  • Recombinant protein applications: Western Blot may be used for other applications determined by the user.
  • Protein Purity: >90%, as determined by SDS-PAGE under reducing conditions.
  • Protein Activity: N/A
  • Protein Tag:  Contains A 6x histidine tag at N-terminus.
  • Protein Formulation: Liquid
  • Source: Produced from E. coli

Human Herpesvirus refers to a group of viruses that cause infections in humans and belong to the herpesviridae family. There are eight known human herpesviruses, including herpes simplex virus 1 and 2, varicella-zoster virus, Epstein-Barr virus, cytomegalovirus, human herpesvirus 6A, 6B, and 7. These viruses can cause a wide range of diseases, including genital herpes, cold sores, chickenpox, mononucleosis, and others. Herpesviruses are highly contagious and are typically spread through direct contact with infected bodily fluids. Once a person is infected, the virus remains in the body for life and can reactivate to cause recurrent outbreaks. There is currently no cure for herpesvirus infections, but antiviral drugs can help control symptoms and reduce the frequency of outbreaks.

Human Herpesvirus antigen refers to any protein or substance found in or produced by human herpesviruses. Herpesvirus antigens are used in diagnostic tests to identify the presence of the virus in a person’s blood or body fluids. The detection of herpesvirus antigens can also help monitor the effectiveness of treatment in people with herpesvirus infections. Additionally, herpesvirus antigens are being studied for their potential use in vaccine development to prevent herpesvirus infections.

The Human Herpesvirus genome refers to the complete set of genetic information contained in the virus. Human herpesviruses have a double-stranded DNA genome that ranges in size from approximately 130 kilobases to more than 220 kilobases. The genome of human herpesviruses encodes for a number of viral proteins that are involved in virus replication, immune evasion, and pathogenesis. The study of human herpesvirus genomes has provided important insights into the biology of these viruses and has been instrumental in the development of antiviral drugs and vaccines.

The virus contains several key proteins that play essential roles in its structure, replication, and pathogenesis. These proteins include:

Capsid protein (Infected cell protein 32, VP26): a protein that makes up the outer layer of the virus particle.

Envelope glycoprotein (B, D, G, H, L): glycoproteins that are found in the viral envelope and are important for viral attachment and entry into host cells.

Glycoprotein (C, D, E, I, K): a type of protein that has a sugar molecule attached to it. In herpesviruses, glycoproteins are found in the viral envelope and play important roles in viral entry, replication, and immune evasion.

Envelope glycoprotein (E, H, I): specific glycoproteins that are found in the herpesvirus envelope and are involved in viral entry and immune evasion.

Neurovirulence factor ICP34.5: a protein that helps herpesviruses evade the host immune response and infect neurons.

Virion host shutoff protein: a protein that is involved in shutting down host protein synthesis during herpesvirus infection.

Immediate-early protein IE4 (IE68): an important regulatory protein that plays a role in activating viral gene expression during the early stages of herpesvirus infection.

VP16: a viral transcription factor that is involved in activating gene expression during the early stages of herpesvirus infection.

Serine/threonine-protein kinase 2: a viral protein kinase that is involved in regulating viral gene expression and replication.

Tegument protein VP22: a viral protein that is found in the tegument layer of the virus particle and is involved in viral replication.

Major capsid protein: a protein that makes up the main structure of the virus particle.

Major capsid scaffold protein: a protein that helps to organize the major capsid proteins into their final structure.

Minor capsid protein binding protein: a protein that is involved in binding to the minor capsid proteins and helping to assemble the virus particle.

Nuclear antigen-3B: a viral protein that is involved in regulating viral gene expression and replication.

Immediate early region: a region of the herpesvirus genome that contains genes that are expressed immediately after infection.

Immediate-early protein 1 (IE1): an important regulatory protein that plays a role in activating viral gene expression during the early stages of herpesvirus infection.

Triplex capsid protein U56: a protein that is involved in the assembly of the virus particle.

VP19C: a viral protein that is involved in capsid assembly and stability.

GP60: a viral glycoprotein that is involved in viral attachment and entry into host cells.

8IE1B protein: a viral protein that is involved in regulating viral gene expression and replication.

IE1A protein: a viral protein that is involved in activating viral gene expression during the early stages of herpesvirus infection.

The use of recombinant proteins/cDNA in academic research and therapeutic applications has skyrocketed. However, in heterologous expression systems, successful recombinant protein expression is dependent on a variety of factors, including codon preference, RNA secondary structure, and GC content. When compared to pre-optimization, more and more experimental results demonstrated that the expression level was dramatically increased, ranging from two to hundred times depending on the gene. Bioclone has created a proprietary technology platform that has resulted in the creation of over 6,000 artificially synthesized codon-optimized cDNA clones (cloned in E.coli expression Vector), which are ready for production of the recombinant proteins.

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