- +1 858 909 0079
- +1 858 909 0057
- [email protected]
- +1 858 909 0079
- [email protected]
Cat. No.
Product Name
Unit Size
Order
Specification
Composition
Magnetic beads are grafted with a high density of cleavable epoxy groups.
Number of Beads
~ 1.68 x 109 beads/mg (1μm beads)
~1.47 x 108 beads/mg (2.5μm beads)
Stability
Short Term (<1 hour): pH 3-11; Long-Term: pH 4-10
Temperature: 4°C -140°C; Most organic solvents
Magnetization
~40-45 EMU/g
Type of Magnetization
Superparamagnetic
Formulation
Lyophilized Powder
Functional Group Density
1μm Magnetic Beads
~255 μmole / g of Beads
2.5μm Magnetic Beads
~240 μmole / g of Beads
Storage
Ship at room temperature. Store 4°C upon receipt.
Introducing BcMag™ Cleavable Epoxy-Activated Magnetic Beads: an innovative solution for your conjugation needs. These uniform magnetic beads are pre-activated with high-density epoxy functional groups on the surface, allowing for the conjugation of both large proteins and small peptides. What sets BcMag™ apart is its ability to covalently conjugate amine, sulfhydryl, or hydroxyl group-containing ligands through its active epoxy group, which is linked to the beads via a built-in cleavable disulfide linker. By utilizing reducing agents like DTT or β-mercaptoethanol, you can easily cleave and separate the target molecule-ligand complex from the beads. But that’s not all – BcMag™ also boasts a hydrophilic surface, ensuring low nonspecific adsorption, excellent dispersion, and easy handling in various buffers. With BcMag™, you can expect precise and reliable results for your research needs.
The beads work perfectly as affinity resin for affinity purification to refine molecules, cells, and parts of cells into purified fractions. After conjugation with ligands, add the beads to a sample containing the target molecules, then mix, incubate, wash and elute the target molecules.
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Pre-activated and ready-to-use
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A cleavable built-in disulfide bond allows the ligand-target molecule complex separated from the beads.
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Stable covalent bond with minimal ligand leakage
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Produces reusable immunoaffinity matrices.
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Low nonspecific binding
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Immobilize 1-10 mg protein or 0.1-1 mg peptide/ml beads.
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Applications: Immunoprecipitation, purification for Antibodies, Proteins/Peptides, DNA/RNA
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